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Nkain3 Gene Detail
Summary
  • Symbol
    Nkain3
  • Name
    Na+/K+ transporting ATPase interacting 3
  • Synonyms
    E130310K16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444830
    NCBI Gene: 269513
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:20118874-20778866 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 4, 7.82 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    19189 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444830
protein coding gene Chr4:20111029-20779990 (-)
129S1/SvImJ ENSMUSG00200001096
protein coding gene Chr4:16793251-17461762 (-)
A/J ENSMUSG00195016163
protein coding gene Chr4:17267644-17936203 (-)
AKR/J ENSMUSG00220001095
protein coding gene Chr4:17021489-17687926 (-)
BALB/cJ ENSMUSG00180001834
protein coding gene Chr4:16745197-17413735 (-)
C3H/HeJ ENSMUSG00175018192
protein coding gene Chr4:17229807-17908213 (-)
C57BL/6NJ ENSMUSG00215009698
protein coding gene Chr4:16888795-17554543 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025842
protein coding gene Chr4:15445441-16063058 (-)
CAST/EiJ ENSTCUG00005016193
protein coding gene Chr4:16902032-17556553 (-)
CBA/J ENSMUSG00210001447
protein coding gene Chr4:16951652-17624004 (-)
DBA/2J ENSMUSG00185000978
protein coding gene Chr4:17061240-17729751 (-)
FVB/NJ ENSMUSG00205001736
protein coding gene Chr4:16608258-17285791 (-)
JF1/MsJ ENSUMUG00000001676
protein coding gene Chr4:17113089-17774830 (-)
LP/J ENSMUSG00230000446
protein coding gene Chr4:20296064-20984262 (-)
NOD/ShiLtJ ENSMUSG00190024400
protein coding gene Chr4:16968564-17637028 (-)
NZO/HlLtJ ENSMUSG00225001753
protein coding gene Chr4:24330063-24973242 (-)
PWK/PhJ ENSLUMG00010001793
protein coding gene Chr4:16574890-17228018 (-)
SPRET/EiJ ENSMSPG00010012372
protein coding gene Chr4:17114163-17760733 (-)
WSB/EiJ ENSIUOG00005008306
protein coding gene Chr4:16677951-17341322 (-)



Homology
more
  • Human Ortholog
    NKAIN3, sodium/potassium transporting ATPase interacting 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NKAIN3, sodium/potassium transporting ATPase interacting 3
  • Synonyms
    FAM77D, NKAIN3-IT1, UG0898H09
  • Links
    NCBI Gene ID: 286183
    UniProt: Q8N8D7

  • Chr Location
    8q12.3; chr8:62248591-63014000 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000055761 Ensembl Gene Model | MGI Sequence Detail 659993 C57BL/6J ±  kb
transcript ENSMUST00000119374 Ensembl | MGI Sequence Detail 4567 Not Applicable  
polypeptide ENSMUSP00000113113 Ensembl | MGI Sequence Detail 181 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000011228 sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3
  • InterPro Domains
    IPR008516 Na,K-Atpase Interacting protein
  • GlyGen
    Q3URJ8 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/01/2026
MGI 6.24
The Jackson Laboratory