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Sirpb1a Gene Detail
Summary
  • Symbol
    Sirpb1a
  • Name
    signal-regulatory protein beta 1A
  • Synonyms
    9930027N05Rik, Sirpb1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444824
    NCBI Gene: 320832
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr3:15436887-15491487 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 3.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    590 from dbSNP Build 142
  • Strain Annotations
    10
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444824
 protein coding gene Chr3:15436713-15491580 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0026796
 protein coding gene Chr3:13024616-13061141 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027499
 protein coding gene Chr3:13476728-13570929 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024861
 protein coding gene Chr3:11040181-11090242 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0026772
 protein coding gene Chr3:13751523-13850859 (-)
DBA/2J MGP_DBA2J_G0026907
 protein coding gene Chr3:12055447-12117613 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0027018
 protein coding gene Chr3:13175918-13355180 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026897
 protein coding gene Chr3:15516118-15562299 (-)
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0025791
 protein coding gene Chr3:12383768-12621120 (-)
WSB/EiJ MGP_WSBEiJ_G0026325
 protein coding gene Chr3:12521630-12560179 (-)



Homology
more
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SIRPB1, signal regulatory protein beta 1
  • Synonyms
    CD172b, SIRP-BETA-1
  • Links
    NCBI Gene ID: 10326
    neXtProt AC: NX_O00241, NX_Q5TFQ8
    UniProt: O00241, Q5TFQ8

  • Chr Location
    20p13; chr20:1561385-1620061 (-)  GRCh38
  • Human Ortholog
    SIRPG, signal regulatory protein gamma
  • Synonyms
    bA77C3.1, CD172g, SIRPB2, SIRP-B2, SIRPgamma
  • Links
    NCBI Gene ID: 55423
    neXtProt AC: NX_Q9P1W8
    UniProt: Q9P1W8

  • Chr Location
    20p13; chr20:1629152-1686455 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320832 NCBI Gene Model | MGI Sequence Detail 54601 C57BL/6J ±  kb
    transcript NM_001002898 RefSeq | MGI Sequence Detail 1232 ZRU/MplStud  
    polypeptide NP_001002898 RefSeq | MGI Sequence Detail 391 ZRU/MplStud  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      Genomic 1
      cDNA 6

      Microarray probesets 5
    References
    more
    • Summaries
      All 25
      Diseases 1
      Gene Ontology 3
      Phenotypes 4
    • Earliest
      J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
    • Latest
      J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory