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Dcaf5 Gene Detail
Summary
  • Symbol
    Dcaf5
  • Name
    DDB1 and CUL4 associated factor 5
  • Synonyms
    9430020B07Rik, BCRG2, BCRP2, mKIAA1824, Wdr22
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444785
    NCBI Gene: 320808
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:80382622-80483375 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 36.61 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2046 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444785
 protein coding gene Chr12:80382622-80483375 (-)
129S1/SvImJ ENSMUSG00200045967
 protein coding gene Chr12:72352681-72453459 (-)
A/J ENSMUSG00195032509
 protein coding gene Chr12:75046208-75147041 (-)
AKR/J ENSMUSG00220048412
 protein coding gene Chr12:72835597-72936418 (-)
BALB/cJ ENSMUSG00180023275
 protein coding gene Chr12:74016881-74117711 (-)
C3H/HeJ ENSMUSG00175038140
 protein coding gene Chr12:77178422-77279244 (-)
C57BL/6NJ ENSMUSG00215045462
 protein coding gene Chr12:73382392-73483154 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017895
 protein coding gene Chr12:74778950-74869369 (-)
CAST/EiJ ENSTCUG00005030716
 protein coding gene Chr12:73315361-73403663 (-)
CBA/J ENSMUSG00210039284
 protein coding gene Chr12:73592685-73693504 (-)
DBA/2J ENSMUSG00185042572
 protein coding gene Chr12:75453438-75554260 (-)
FVB/NJ ENSMUSG00205021485
 protein coding gene Chr12:73199645-73293506 (-)
JF1/MsJ ENSUMUG00000013879
 protein coding gene Chr12:79442711-79532571 (-)
LP/J ENSMUSG00230043438
 protein coding gene Chr12:82470788-82571563 (-)
NOD/ShiLtJ ENSMUSG00190028959
 protein coding gene Chr12:72656170-72750024 (-)
NZO/HlLtJ ENSMUSG00225050862
 protein coding gene Chr12:84524281-84624241 (-)
PWK/PhJ ENSLUMG00010023537
 protein coding gene Chr12:73459197-73549167 (-)
SPRET/EiJ ENSMSPG00010016058
 protein coding gene Chr12:75274711-75370166 (-)
WSB/EiJ ENSIUOG00005040831
 protein coding gene Chr12:73265425-73366178 (-)



Homology
more
  • Human Ortholog
    DCAF5, DDB1 and CUL4 associated factor 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCAF5, DDB1 and CUL4 associated factor 5
  • Synonyms
    BCRG2, BCRP2, D14S1461E, WDR22
  • Links
    NCBI Gene ID: 8816
    UniProt: Q96JK2

  • Chr Location
    14q24.1; chr14:69050881-69153197 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    13
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 320808 NCBI Gene Model | MGI Sequence Detail 100754 C57BL/6J ±  kb
    transcript NM_177267 RefSeq | MGI Sequence Detail 5706 C57BL/6  
    polypeptide Q80T85 UniProt | EBI | MGI Sequence Detail 946 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:2144792, MGI:2144823, MGI:2144898, MGI:2145009
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 1
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:380627 Masuda S, et al., TRAF7 determines circadian period through ubiquitination and degradation of DBP. Commun Biol. 2024 Oct 8;7(1):1280
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory