About   Help   FAQ
Zfp420 Gene Detail
Summary
  • Symbol
    Zfp420
  • Name
    zinc finger protein 420
  • Synonyms
    B230312I18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444666
    NCBI Gene: 233058
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:29559404-29576717 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 17.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    742 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444666
 protein coding gene Chr7:29559392-29576727 (+)
129S1/SvImJ ENSMUSG00200043497
 protein coding gene Chr7:19342005-19359193 (+)
A/J ENSMUSG00195043825
 protein coding gene Chr7:22014990-22030218 (+)
AKR/J ENSMUSG00220044417
 protein coding gene Chr7:22457177-22472399 (-)
BALB/cJ ENSMUSG00180053232
 protein coding gene Chr7:20074438-20089664 (+)
C3H/HeJ ENSMUSG00175035528
 protein coding gene Chr7:21117121-21134437 (+)
C57BL/6NJ ENSMUSG00215054050
 protein coding gene Chr7:19249784-19267094 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029490
 protein coding gene Chr7:29090124-29111929 (+)
CAST/EiJ ENSTCUG00005048363
 protein coding gene Chr7:21049235-21064727 (+)
CBA/J ENSMUSG00210025130
 protein coding gene Chr7:20310327-20327639 (+)
DBA/2J ENSMUSG00185041887
 protein coding gene Chr7:23405643-23420869 (+)
FVB/NJ ENSMUSG00205017834
 protein coding gene Chr7:20059291-20076608 (+)
JF1/MsJ ENSUMUG00000051839
 protein coding gene Chr7:27821046-27836258 (+)
LP/J ENSMUSG00230051978
 protein coding gene Chr7:28576089-28591985 (+)
NOD/ShiLtJ ENSMUSG00190035692
 protein coding gene Chr7:19737050-19754336 (+)
NZO/HlLtJ no annotation
PWK/PhJ ENSLUMG00010035556
 protein coding gene Chr7:19779301-19794464 (+)
SPRET/EiJ ENSMSPG00010049057
 protein coding gene Chr7:19165028-19167674 (+)
WSB/EiJ ENSIUOG00005053546
 protein coding gene Chr7:14030985-14048276 (+)



Homology
more
  • Human Ortholog
    ZNF420, zinc finger protein 420
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF420, zinc finger protein 420
  • Synonyms
    APAK
  • Links
    NCBI Gene ID: 147923
    UniProt: Q8TAQ5

  • Chr Location
    19q13.12; chr19:37007823-37130368 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    649
  • Tissues
    39
  • cDNA Data
    20
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000058402 Ensembl Gene Model | MGI Sequence Detail 17314 C57BL/6J ±  kb
transcript ENSMUST00000074876 Ensembl | MGI Sequence Detail 2537 Not Applicable  
polypeptide ENSMUSP00000074417 Ensembl | MGI Sequence Detail 578 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR050589 Ikaros C2H2-type zinc-finger
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 21
    cDNA 20
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:48249 Agata Y, et al., Rapid and efficient cloning of cDNAs encoding Kruppel-like zinc finger proteins by degenerate PCR. Gene. 1998 Jun 15;213(1-2):55-64
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory