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Sgtb Gene Detail
Summary
  • Symbol
    Sgtb
  • Name
    small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
  • Synonyms
    C630001O05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444615
    NCBI Gene: 218544
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:104246249-104278243 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 56.23 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1086 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444615
 protein coding gene Chr13:104246233-104278369 (+)
129S1/SvImJ ENSMUSG00200008109
 protein coding gene Chr13:98660129-98692401 (+)
A/J ENSMUSG00195028932
 protein coding gene Chr13:99253237-99285505 (+)
AKR/J ENSMUSG00220025940
 protein coding gene Chr13:97674366-97706636 (+)
BALB/cJ ENSMUSG00180036126
 protein coding gene Chr13:99807590-99839863 (+)
C3H/HeJ ENSMUSG00175016848
 protein coding gene Chr13:99890563-99922537 (+)
C57BL/6NJ ENSMUSG00215028784
 protein coding gene Chr13:99893359-99925366 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018858
 protein coding gene Chr13:97680549-97713812 (+)
CAST/EiJ ENSTCUG00005011265
 protein coding gene Chr13:99015749-99047483 (+)
CBA/J ENSMUSG00210010772
 protein coding gene Chr13:99211525-99243498 (+)
DBA/2J ENSMUSG00185026396
 protein coding gene Chr13:102970252-103002258 (+)
FVB/NJ ENSMUSG00205017869
 protein coding gene Chr13:98658735-98691015 (+)
JF1/MsJ ENSUMUG00000009895
 protein coding gene Chr13:102565102-102597083 (+)
LP/J ENSMUSG00230005668
 protein coding gene Chr13:113129859-113162131 (+)
NOD/ShiLtJ ENSMUSG00190036984
 protein coding gene Chr13:99568362-99600634 (+)
NZO/HlLtJ ENSMUSG00225037167
 protein coding gene Chr13:105462730-105497354 (+)
PWK/PhJ ENSLUMG00010024966
 protein coding gene Chr13:98613827-98645794 (+)
SPRET/EiJ ENSMSPG00010008792
 protein coding gene Chr13:100021236-100053013 (+)
WSB/EiJ ENSIUOG00005030761
 protein coding gene Chr13:98652851-98685153 (+)



Homology
more
  • Human Ortholog
    SGTB, small glutamine rich tetratricopeptide repeat co-chaperone beta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SGTB, small glutamine rich tetratricopeptide repeat co-chaperone beta
  • Synonyms
    SGT2
  • Links
    NCBI Gene ID: 54557
    UniProt: Q96EQ0

  • Chr Location
    5q12.3; chr5:65665928-65723035 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    694
  • Tissues
    19
  • cDNA Data
    30
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000042743 Ensembl Gene Model | MGI Sequence Detail 31995 C57BL/6J ±  kb
    transcript ENSMUST00000044385 Ensembl | MGI Sequence Detail 3048 Not Applicable  
    polypeptide ENSMUSP00000041307 Ensembl | MGI Sequence Detail 304 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 30
      cDNA 30

      Microarray probesets 3
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 8
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory