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Ralgapb Gene Detail
Summary
  • Symbol
    Ralgapb
  • Name
    Ral GTPase activating protein, beta subunit (non-catalytic)
  • Synonyms
    B230339M05Rik, mKIAA1219
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444531
    NCBI Gene: 228850
  • Alliance
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:158251768-158341173 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 78.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    405 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444531
protein coding gene Chr2:158251722-158341173 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026794
protein coding gene Chr2:163486168-163576728 (+)
A/J MGP_AJ_G0026760
protein coding gene Chr2:156924503-157013286 (+)
AKR/J MGP_AKRJ_G0026731
protein coding gene Chr2:161548877-161639774 (+)
BALB/cJ MGP_BALBcJ_G0026769
protein coding gene Chr2:157230137-157319174 (+)
C3H/HeJ MGP_C3HHeJ_G0026511
protein coding gene Chr2:161888383-161989702 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027218
protein coding gene Chr2:168359755-168458106 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024588
protein coding gene Chr2:150366028-150455055 (+)
CAST/EiJ MGP_CASTEiJ_G0025973
protein coding gene Chr2:162243326-162331617 (+)
CBA/J MGP_CBAJ_G0026488
protein coding gene Chr2:174392166-174485738 (+)
DBA/2J MGP_DBA2J_G0026626
protein coding gene Chr2:156100824-156190184 (+)
FVB/NJ MGP_FVBNJ_G0026593
protein coding gene Chr2:154509992-154599674 (+)
LP/J MGP_LPJ_G0026729
protein coding gene Chr2:163575987-163667666 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026614
protein coding gene Chr2:178183707-178277964 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027274
protein coding gene Chr2:161380795-161471209 (+)
PWK/PhJ MGP_PWKPhJ_G0025707
protein coding gene Chr2:155635102-155725076 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025510
protein coding gene Chr2:160303452-160393052 (+)
WSB/EiJ MGP_WSBEiJ_G0026043
protein coding gene Chr2:162273721-162365314 (+)



Homology
more
  • Human Ortholog
    RALGAPB, Ral GTPase activating protein non-catalytic subunit beta
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RALGAPB, Ral GTPase activating protein non-catalytic subunit beta
  • Synonyms
    KIAA1219, RalGAPbeta
  • Links
    NCBI Gene ID: 57148
    neXtProt AC: NX_Q86X10
    UniProt: Q86X10

  • Chr Location
    20q11.23; chr20:38472816-38578859 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027652 Ensembl Gene Model | MGI Sequence Detail 89406 C57BL/6J ±  kb
    transcript ENSMUST00000109485 Ensembl | MGI Sequence Detail 6709 Not Applicable  
    polypeptide ENSMUSP00000105111 Ensembl | MGI Sequence Detail 1507 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 14

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2138996
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 10
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory