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Iffo1 Gene Detail
Summary
  • Symbol
    Iffo1
  • Name
    intermediate filament family orphan 1
  • Synonyms
    4733401N06Rik, A930037G23Rik, Iffo
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444516
    NCBI Gene: 320678
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:125122204-125138745 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 59.32 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    459 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444516
 protein coding gene Chr6:125122167-125138746 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031287
 protein coding gene Chr6:128476174-128493183 (+)
A/J MGP_AJ_G0031257
 protein coding gene Chr6:123629854-123646421 (+)
AKR/J MGP_AKRJ_G0031185
 protein coding gene Chr6:127005491-127022523 (+)
BALB/cJ MGP_BALBcJ_G0031265
 protein coding gene Chr6:123226907-123243525 (+)
C3H/HeJ MGP_C3HHeJ_G0030988
 protein coding gene Chr6:127066942-127094588 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031721
 protein coding gene Chr6:131854088-131871351 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028870
 protein coding gene Chr6:120836111-120851885 (+)
CAST/EiJ MGP_CASTEiJ_G0030369
 protein coding gene Chr6:127274472-127297322 (+)
CBA/J MGP_CBAJ_G0030949
 protein coding gene Chr6:136916927-136933398 (+)
DBA/2J MGP_DBA2J_G0031105
 protein coding gene Chr6:122560745-122577426 (+)
FVB/NJ MGP_FVBNJ_G0031055
 protein coding gene Chr6:121469989-121491679 (+)
LP/J MGP_LPJ_G0031185
 protein coding gene Chr6:128640828-128658229 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031093
 protein coding gene Chr6:140948120-140965232 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031756
 protein coding gene Chr6:126907512-126924001 (+)
PWK/PhJ MGP_PWKPhJ_G0030084
 protein coding gene Chr6:120803725-120820558 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029913
 protein coding gene Chr6:124983001-124999174 (+)
WSB/EiJ MGP_WSBEiJ_G0030454
 protein coding gene Chr6:127275461-127294207 (+)



Homology
more
  • Human Ortholog
    IFFO1, intermediate filament family orphan 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFFO1, intermediate filament family orphan 1
  • Synonyms
    HOM-TES-103, IFFO
  • Links
    NCBI Gene ID: 25900
    UniProt: Q0D2I5

  • Chr Location
    12p13.31; chr12:6538961-6556073 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    796
  • Tissues
    7
  • cDNA Data
    42
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038271 Ensembl Gene Model | MGI Sequence Detail 16542 C57BL/6J ±  kb
transcript ENSMUST00000117675 Ensembl | MGI Sequence Detail 2833 Not Applicable  
polypeptide ENSMUSP00000113088 Ensembl | MGI Sequence Detail 562 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000032187 non-homologous end joining factor IFFO1
    (term hierarchy)
  • InterPro Domains
    IPR039008 Intermediate filament, rod domain
  • GlyGen
    Q8BXL9 14 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (13 sites)
Molecular
Reagents
less
  • All nucleic 43
    cDNA 43

    Microarray probesets 4
Other
Accession IDs
less
MGI:1918072
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory