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Fsd2 Gene Detail
Summary
  • Symbol
    Fsd2
  • Name
    fibronectin type III and SPRY domain containing 2
  • Synonyms
    9830160G03Rik, Spryd1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444310
    NCBI Gene: 244091
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:81184102-81216729 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 45.71 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    437 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444310
 protein coding gene Chr7:81183056-81216729 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032431
 protein coding gene Chr7:83598918-83633845 (-)
A/J MGP_AJ_G0032410
 protein coding gene Chr7:81621167-81656998 (-)
AKR/J MGP_AKRJ_G0032346
 protein coding gene Chr7:83424809-83461812 (-)
BALB/cJ MGP_BALBcJ_G0032422
 protein coding gene Chr7:81281114-81315402 (-)
C3H/HeJ MGP_C3HHeJ_G0032135
 protein coding gene Chr7:84041517-84078493 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032914
 protein coding gene Chr7:86860789-86899705 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029922
 protein coding gene Chr7:84095714-84130123 (-)
CAST/EiJ MGP_CASTEiJ_G0031463
 protein coding gene Chr7:74975702-75012078 (-)
CBA/J MGP_CBAJ_G0032101
 protein coding gene Chr7:89772745-89808933 (-)
DBA/2J MGP_DBA2J_G0032256
 protein coding gene Chr7:80153022-80187219 (-)
FVB/NJ MGP_FVBNJ_G0032211
 protein coding gene Chr7:80093316-80127715 (-)
LP/J MGP_LPJ_G0032337
 protein coding gene Chr7:84830959-84865435 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032248
 protein coding gene Chr7:89836459-89870221 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032932
 protein coding gene Chr7:82836405-82873902 (-)
PWK/PhJ MGP_PWKPhJ_G0031183
 protein coding gene Chr7:73367522-73401611 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031025
 protein coding gene Chr7:69845402-69883114 (-)
WSB/EiJ MGP_WSBEiJ_G0031581
 protein coding gene Chr7:83200451-83236388 (-)



Homology
more
  • Human Ortholog
    FSD2, fibronectin type III and SPRY domain containing 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FSD2, fibronectin type III and SPRY domain containing 2
  • Synonyms
    SPRYD1
  • Links
    NCBI Gene ID: 123722
    neXtProt AC: NX_A1L4K1
    UniProt: A1L4K1

  • Chr Location
    chr15:82755362-82806070 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotypes from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    7
  • cDNA Data
    11
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 244091 NCBI Gene Model | MGI Sequence Detail 32628 C57BL/6J ±  kb
    transcript NM_172904 RefSeq | MGI Sequence Detail 2976 C57BL/6  
    polypeptide Q8BZ52 UniProt | EBI | MGI Sequence Detail 716 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 11

      Microarray probesets 3
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Gene Ontology 2
      Phenotypes 17
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory