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Ankrd27 Gene Detail
Summary
  • Symbol
    Ankrd27
  • Name
    ankyrin repeat domain 27
  • Synonyms
    D330003H11Rik, MGC:25907, Varp
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444103
    NCBI Gene: 245886
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:35285669-35338651 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 21.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1967 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444103
 protein coding gene Chr7:35285652-35338662 (+)
129S1/SvImJ ENSMUSG00200024801
 protein coding gene Chr7:24042490-24090024 (+)
A/J ENSMUSG00195038151
 protein coding gene Chr7:27014406-27062079 (+)
AKR/J ENSMUSG00220026401
 protein coding gene Chr7:14838370-14885944 (+)
BALB/cJ ENSMUSG00180014615
 protein coding gene Chr7:24570464-24618129 (+)
C3H/HeJ ENSMUSG00175032431
 protein coding gene Chr7:25088051-25135585 (+)
C57BL/6NJ ENSMUSG00215019797
 protein coding gene Chr7:24447497-24495038 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029590
 protein coding gene Chr7:34809160-34860422 (+)
CAST/EiJ ENSTCUG00005041567
 protein coding gene Chr7:26200928-26249144 (+)
CBA/J ENSMUSG00210024869
 protein coding gene Chr7:25106848-25154382 (+)
DBA/2J ENSMUSG00185040420
 protein coding gene Chr7:27872513-27920141 (+)
FVB/NJ ENSMUSG00205012068
 protein coding gene Chr7:24850758-24898409 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230012215
 protein coding gene Chr7:33546637-33594241 (+)
NOD/ShiLtJ ENSMUSG00190008520
 protein coding gene Chr7:24713012-24760626 (+)
NZO/HlLtJ ENSMUSG00225008162
 protein coding gene Chr7:31898453-31960929 (+)
PWK/PhJ ENSLUMG00010020409
 protein coding gene Chr7:24276719-24332783 (+)
SPRET/EiJ ENSMSPG00010005476
 protein coding gene Chr7:24322241-24374480 (+)
WSB/EiJ ENSIUOG00005007501
 protein coding gene Chr7:24892386-24939843 (+)



Homology
more
  • Human Ortholog
    ANKRD27, ankyrin repeat domain 27
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKRD27, ankyrin repeat domain 27
  • Synonyms
    PP12899, VARP
  • Links
    NCBI Gene ID: 84079
    UniProt: Q96NW4

  • Chr Location
    19q13.11; chr19:32597000-32676597 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human ANKRD27 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    58
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    614
  • Tissues
    17
  • cDNA Data
    81
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034867 Ensembl Gene Model | MGI Sequence Detail 52983 C57BL/6J ±  kb
    transcript ENSMUST00000040844 Ensembl | MGI Sequence Detail 4284 Not Applicable  
    polypeptide ENSMUSP00000041751 Ensembl | MGI Sequence Detail 1048 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 83
      cDNA 82
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2141812, MGI:2384295
    References
    more
    • Summaries
      All 53
      Developmental Gene Expression 1
      Gene Ontology 12
      Phenotypes 12
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory