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Rnf152 Gene Detail
Summary
  • Symbol
    Rnf152
  • Name
    ring finger protein 152
  • Synonyms
    A930029B02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443787
    NCBI Gene: 320311
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:105204639-105284435 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 49.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2282 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443787
 protein coding gene Chr1:105204639-105284665 (-)
129S1/SvImJ ENSMUSG00200000326
 protein coding gene Chr1:102482535-102577645 (-)
A/J ENSMUSG00195007646
 protein coding gene Chr1:101965029-102052039 (-)
AKR/J ENSMUSG00220000173
 protein coding gene Chr1:102043430-102130454 (-)
BALB/cJ ENSMUSG00180000280
 protein coding gene Chr1:102252347-102339350 (-)
C3H/HeJ ENSMUSG00175000547
 protein coding gene Chr1:102174585-102268450 (-)
C57BL/6NJ ENSMUSG00215006641
 protein coding gene Chr1:102198833-102278841 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014482
 protein coding gene Chr1:98013662-98089525 (-)
CAST/EiJ ENSTCUG00005002779
 protein coding gene Chr1:101554186-101633997 (-)
CBA/J ENSMUSG00210000105
 protein coding gene Chr1:102055836-102149699 (-)
DBA/2J ENSMUSG00185007830
 protein coding gene Chr1:106508839-106600893 (-)
FVB/NJ ENSMUSG00205007883
 protein coding gene Chr1:101345866-101433730 (-)
JF1/MsJ ENSUMUG00000000138
 protein coding gene Chr1:105127458-105207255 (-)
LP/J ENSMUSG00230000054
 protein coding gene Chr1:105771703-105863756 (-)
NOD/ShiLtJ ENSMUSG00190000228
 protein coding gene Chr1:102138493-102230547 (-)
NZO/HlLtJ ENSMUSG00225000305
 protein coding gene Chr1:109657179-109745012 (-)
PWK/PhJ ENSLUMG00010000098
 protein coding gene Chr1:101547435-101630038 (-)
SPRET/EiJ ENSMSPG00010000448
 protein coding gene Chr1:103809265-103882312 (-)
WSB/EiJ ENSIUOG00005000978
 protein coding gene Chr1:101855369-101942250 (-)



Homology
more
  • Human Ortholog
    RNF152, ring finger protein 152
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNF152, ring finger protein 152
  • Links
    NCBI Gene ID: 220441
    UniProt: Q8N8N0

  • Chr Location
    18q21.33; chr18:61808067-61895097 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    3 involving Rnf152
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    9 strains or lines available
Mice homozygous for a null mutation display reduced starvation induced autophagy in MEFs.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    60
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    631
  • Tissues
    34
  • cDNA Data
    23
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047496 Ensembl Gene Model | MGI Sequence Detail 79797 C57BL/6J ±  kb
transcript ENSMUST00000058688 Ensembl | MGI Sequence Detail 8492 Not Applicable  
polypeptide ENSMUSP00000050103 Ensembl | MGI Sequence Detail 203 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    Genomic 2
    cDNA 23

    Microarray probesets 1
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 10
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:285783 Xiong MG, et al., RNF152 positively regulates TLR/IL-1R signaling by enhancing MyD88 oligomerization. EMBO Rep. 2020 Mar 4;21(3):e48860
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory