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Mrm1 Gene Detail
Summary
  • Symbol
    Mrm1
  • Name
    mitochondrial rRNA methyltransferase 1
  • Synonyms
    A530065E19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443470
    NCBI Gene: 217038
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:84703887-84710341 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 51.34 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    101 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443470
 protein coding gene Chr11:84703887-84710341 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018871
 protein coding gene Chr11:86262269-86268689 (-)
A/J MGP_AJ_G0018838
 protein coding gene Chr11:82971577-82977996 (-)
AKR/J MGP_AKRJ_G0018808
 protein coding gene Chr11:85425950-85434375 (-)
BALB/cJ MGP_BALBcJ_G0018811
 protein coding gene Chr11:83360431-83367311 (-)
C3H/HeJ MGP_C3HHeJ_G0018625
 protein coding gene Chr11:85483911-85490322 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019263
 protein coding gene Chr11:88885938-88892354 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016896
 protein coding gene Chr11:80059173-80066013 (-)
CAST/EiJ MGP_CASTEiJ_G0018180
 protein coding gene Chr11:86119675-86126132 (-)
CBA/J MGP_CBAJ_G0018596
 protein coding gene Chr11:92648199-92659270 (-)
DBA/2J MGP_DBA2J_G0018704
 protein coding gene Chr11:82543624-82551040 (-)
FVB/NJ MGP_FVBNJ_G0018693
 protein coding gene Chr11:82038222-82044636 (-)
LP/J MGP_LPJ_G0018774
 protein coding gene Chr11:86789120-86795559 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018720
 protein coding gene Chr11:92798422-92806683 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019303
 protein coding gene Chr11:85704383-85710841 (-)
PWK/PhJ MGP_PWKPhJ_G0017949
 protein coding gene Chr11:83317380-83324446 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017741
 protein coding gene Chr11:85251614-85261756 (-)
WSB/EiJ MGP_WSBEiJ_G0018231
 protein coding gene Chr11:85547789-85554243 (-)



Homology
more
  • Human Ortholog
    MRM1, mitochondrial rRNA methyltransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRM1, mitochondrial rRNA methyltransferase 1
  • Links
    NCBI Gene ID: 79922
    neXtProt AC: NX_Q6IN84
    UniProt: Q6IN84

  • Chr Location
    17q12; chr17:36601583-36634698 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    30
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 217038 NCBI Gene Model | MGI Sequence Detail 6455 C57BL/6J ±  kb
transcript NM_145433 RefSeq | MGI Sequence Detail 2490 Not Specified  
polypeptide Q99J25 UniProt | EBI | MGI Sequence Detail 320 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010568 rRNA methyltransferase 1, mitochondrial
    (term hierarchy)
  • EC
    2.1.1.-
  • InterPro Domains
    IPR029028 Alpha/beta knot methyltransferases
    IPR029064 Ribosomal protein eL30-like superfamily
    IPR013123 RNA 2-O ribose methyltransferase, substrate binding
    IPR047261 rRNA methyltransferase 1, methyltransferase domain
    IPR047182 rRNA methyltransferase 1, mitochondrial
    IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal
    IPR001537 tRNA/rRNA methyltransferase, SpoU type
Molecular
Reagents
less
  • All nucleic 33
    Genomic 1
    cDNA 32

    Microarray probesets 4
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 16
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory