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Gk5 Gene Detail
Summary
  • Symbol
    Gk5
  • Name
    glycerol kinase 5
  • Synonyms
    C330018K18Rik, G630067D24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443336
    NCBI Gene: 235533
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:96001415-96066661 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 50.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1973 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443336
 protein coding gene Chr9:96001379-96066680 (+)
129S1/SvImJ ENSMUSG00200015839
 protein coding gene Chr9:93117525-93182845 (+)
A/J ENSMUSG00195017523
 protein coding gene Chr9:92385003-92450341 (+)
AKR/J ENSMUSG00220036533
 protein coding gene Chr9:92731830-92797182 (+)
BALB/cJ ENSMUSG00180019223
 protein coding gene Chr9:92704595-92769924 (+)
C3H/HeJ ENSMUSG00175011202
 protein coding gene Chr9:93044603-93109930 (+)
C57BL/6NJ ENSMUSG00215016597
 protein coding gene Chr9:93017477-93082740 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032536
 protein coding gene Chr9:91722457-91739036 (+)
CAST/EiJ ENSTCUG00005012817
 protein coding gene Chr9:92868666-92934458 (+)
CBA/J ENSMUSG00210015111
 protein coding gene Chr9:92886605-92951931 (+)
DBA/2J ENSMUSG00185011674
 protein coding gene Chr9:93072703-93138020 (+)
FVB/NJ ENSMUSG00205015383
 protein coding gene Chr9:93077494-93142827 (+)
JF1/MsJ ENSUMUG00000039308
 protein coding gene Chr9:92773187-92838258 (+)
LP/J ENSMUSG00230019073
 protein coding gene Chr9:93241056-93306375 (+)
NOD/ShiLtJ ENSMUSG00190028380
 protein coding gene Chr9:92704067-92769343 (+)
NZO/HlLtJ ENSMUSG00225019559
 protein coding gene Chr9:93348981-93414040 (+)
PWK/PhJ ENSLUMG00010026133
 protein coding gene Chr9:92770325-92835547 (+)
SPRET/EiJ ENSMSPG00010003635
 protein coding gene Chr9:94583984-94651398 (+)
WSB/EiJ ENSIUOG00005021085
 protein coding gene Chr9:92145968-92211287 (+)



Homology
more
  • Human Ortholog
    GK5, glycerol kinase 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GK5, glycerol kinase 5
  • Links
    NCBI Gene ID: 256356
    UniProt: Q6ZS86

  • Chr Location
    3q23; chr3:142157527-142225592 (-)  GRCh38
  • MGI Vertebrate Homology
    Gk5 stringent orthology
    1 human;1 mouse;1 rat;1 zebrafish
  • HCOP
    vertebrate homology predictions: GK5
  • Protein SuperFamily
    GlpK
  • Gene Tree
    Gk5
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotypes from 6 alleles in 6 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for ENU-induced alleles exhibit skin phenotype and alopecia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    612
  • Tissues
    2
  • cDNA Data
    37
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000041440 Ensembl Gene Model | MGI Sequence Detail 65247 C57BL/6J ±  kb
    transcript ENSMUST00000085217 Ensembl | MGI Sequence Detail 2815 Not Applicable  
    polypeptide ENSMUSP00000082313 Ensembl | MGI Sequence Detail 534 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 37
      cDNA 37

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2444291, MGI:3034778
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 1
      Gene Ontology 7
      Phenotypes 12
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:243852 Zhang D, et al., Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5. Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5197-E5206
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory