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Rims3 Gene Detail
Summary
  • Symbol
    Rims3
  • Name
    regulating synaptic membrane exocytosis 3
  • Synonyms
    A730060M23Rik, mKIAA0237, Nim3, Rim3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443331
    NCBI Gene: 242662
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:120712013-120753776 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 56.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1046 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443331
 protein coding gene Chr4:120711976-120753777 (+)
129S1/SvImJ ENSMUSG00200012943
 protein coding gene Chr4:114619004-114661369 (+)
A/J ENSMUSG00195028143
 protein coding gene Chr4:115851292-115893665 (+)
AKR/J ENSMUSG00220021773
 protein coding gene Chr4:115240043-115282410 (+)
BALB/cJ ENSMUSG00180043925
 protein coding gene Chr4:113907436-113949575 (+)
C3H/HeJ ENSMUSG00175024458
 protein coding gene Chr4:114920580-114962723 (+)
C57BL/6NJ ENSMUSG00215033320
 protein coding gene Chr4:116051848-116094218 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026416
 protein coding gene Chr4:111379376-111420347 (+)
CAST/EiJ ENSTCUG00005040940
 protein coding gene Chr4:114734146-114775814 (+)
CBA/J ENSMUSG00210051777
 protein coding gene Chr4:114527006-114569150 (+)
DBA/2J ENSMUSG00185040407
 protein coding gene Chr4:116082048-116124188 (+)
FVB/NJ ENSMUSG00205012552
 protein coding gene Chr4:114007982-114050359 (+)
JF1/MsJ ENSUMUG00000005130
 protein coding gene Chr4:115999740-116041343 (+)
LP/J ENSMUSG00230039580
 protein coding gene Chr4:119437290-119479658 (+)
NOD/ShiLtJ ENSMUSG00190029867
 protein coding gene Chr4:113920404-113962541 (+)
NZO/HlLtJ ENSMUSG00225014483
 protein coding gene Chr4:124982729-125025090 (+)
PWK/PhJ ENSLUMG00010039705
 protein coding gene Chr4:113403350-113445479 (+)
SPRET/EiJ ENSMSPG00010033698
 protein coding gene Chr4:115507513-115532010 (+)
WSB/EiJ ENSIUOG00005042488
 protein coding gene Chr4:114234405-114276821 (+)



Homology
more
  • Human Ortholog
    RIMS3, regulating synaptic membrane exocytosis 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RIMS3, regulating synaptic membrane exocytosis 3
  • Synonyms
    NIM3, RIM 3, RIM3
  • Links
    NCBI Gene ID: 9783
    UniProt: Q9UJD0

  • Chr Location
    1p34.2; chr1:40620679-40692066 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice exhibit normal hearing.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    606
  • Tissues
    7
  • cDNA Data
    40
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032890 Ensembl Gene Model | MGI Sequence Detail 41764 C57BL/6J ±  kb
transcript ENSMUST00000071093 Ensembl | MGI Sequence Detail 6505 Not Applicable  
polypeptide ENSMUSP00000068178 Ensembl | MGI Sequence Detail 307 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 40

    Microarray probesets 2
References
more
  • Summaries
    All 46
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 14
  • Earliest
    J:66000 Cheung KJ Jr, et al., Expression of the novel tumour suppressor p33(ING1)is independent of p53. Br J Cancer. 2000 Dec;83(11):1468-72
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory