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Fbxw21 Gene Detail
Summary
  • Symbol
    Fbxw21
  • Name
    F-box and WD-40 domain protein 21
  • Synonyms
    E330009P21Rik
Location &
Maps
more
  • Sequence Map
    Chr9:108968522-108991090 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.63 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    732 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443323
 protein coding gene Chr9:108968515-108991109 (-)
129S1/SvImJ ENSMUSG00200039396
 protein coding gene Chr9:106165301-106187901 (-)
A/J ENSMUSG00195033211
 protein coding gene Chr9:105384541-105407144 (-)
AKR/J ENSMUSG00220025995
 protein coding gene Chr9:105771862-105794462 (-)
BALB/cJ ENSMUSG00180026998
 protein coding gene Chr9:105701015-105723615 (-)
C3H/HeJ ENSMUSG00175031400
 protein coding gene Chr9:106043259-106065861 (-)
C57BL/6NJ ENSMUSG00215021554
 protein coding gene Chr9:106021839-106044432 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005023681
 protein coding gene Chr9:105795677-105819353 (-)
CBA/J ENSMUSG00210030455
 protein coding gene Chr9:105893455-105917102 (-)
DBA/2J ENSMUSG00185039434
 protein coding gene Chr9:106052690-106075291 (-)
FVB/NJ ENSMUSG00205046773
 protein coding gene Chr9:106062622-106085272 (-)
JF1/MsJ ENSUMUG00000052882
 protein coding gene Chr9:105882841-105906513 (-)
LP/J ENSMUSG00230044701
 protein coding gene Chr9:106194090-106216689 (-)
NOD/ShiLtJ ENSMUSG00190026679
 protein coding gene Chr9:105691091-105713692 (-)
NZO/HlLtJ ENSMUSG00225023507
 protein coding gene Chr9:106426424-106449177 (-)
PWK/PhJ ENSLUMG00010038623
 protein coding gene Chr9:105846905-105870566 (-)
SPRET/EiJ ENSMSPG00010032109
 protein coding gene Chr9:107676159-107699908 (-)
WSB/EiJ ENSIUOG00005045663
 protein coding gene Chr9:105146248-105168847 (-)



Homology
more
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXW12, F-box and WD repeat domain containing 12
  • Synonyms
    FBW12, FBXO12, FBXO35
  • Links
    NCBI Gene ID: 285231
    UniProt: Q6X9E4

  • Chr Location
    3p21.31; chr3:48372219-48401259 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    615
  • Tissues
    13
  • cDNA Data
    9
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 320082 NCBI Gene Model | MGI Sequence Detail 22569 C57BL/6J ±  kb
transcript NM_001382229 RefSeq | MGI Sequence Detail 2240 C57BL/6  
polypeptide Q8BI38 UniProt | EBI | MGI Sequence Detail 468 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • PDB
    9XRL
  • InterPro Domains
    IPR001810 F-box domain
    IPR036047 F-box-like domain superfamily
    IPR052121 F-box Protein Family Substrate Recognition Components
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory