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Agbl2 Gene Detail
Summary
  • Symbol
    Agbl2
  • Name
    ATP/GTP binding protein-like 2
  • Synonyms
    A430081C19Rik, Ccp2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443254
    NCBI Gene: 271813
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:90613071-90664781 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 50.37 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    178 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443254
protein coding gene Chr2:90613029-90664781 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026132
protein coding gene Chr2:92058051-92119462 (+)
A/J MGP_AJ_G0026093
protein coding gene Chr2:88388654-88440963 (+)
AKR/J MGP_AKRJ_G0026074
protein coding gene Chr2:90832144-90886252 (+)
BALB/cJ MGP_BALBcJ_G0026102
protein coding gene Chr2:88547613-88602252 (+)
C3H/HeJ MGP_C3HHeJ_G0025853
protein coding gene Chr2:91106729-91162468 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026553
protein coding gene Chr2:95299433-95365481 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023943
protein coding gene Chr2:84910808-84958103 (+)
CAST/EiJ MGP_CASTEiJ_G0025318
protein coding gene Chr2:91618149-91682461 (+)
CBA/J MGP_CBAJ_G0025831
protein coding gene Chr2:98544622-98608380 (+)
DBA/2J MGP_DBA2J_G0025967
protein coding gene Chr2:87985683-88037194 (+)
FVB/NJ MGP_FVBNJ_G0025930
protein coding gene Chr2:87083370-87136651 (+)
LP/J MGP_LPJ_G0026071
protein coding gene Chr2:92266960-92325889 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025956
protein coding gene Chr2:101600569-101663406 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026607
protein coding gene Chr2:90880208-90940638 (+)
PWK/PhJ MGP_PWKPhJ_G0025053
protein coding gene Chr2:87706449-87761119 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024854
protein coding gene Chr2:90472254-90528574 (+)
WSB/EiJ MGP_WSBEiJ_G0025385
protein coding gene Chr2:91471085-91529153 (+)



Homology
more
  • Human Ortholog
    AGBL2, AGBL carboxypeptidase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AGBL2, AGBL carboxypeptidase 2
  • Synonyms
    CCP2
  • Links
    NCBI Gene ID: 79841
    neXtProt AC: NX_Q5U5Z8
    UniProt: Q5U5Z8

  • Chr Location
    11p11.2; chr11:47659591-47715389 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 3 alleles in 3 genetic backgrounds
    1 phenotype from multigenic genotypes
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice for a targeted allele are viable and fertile. Mice exhibit normal response to herpes simplex virus (HSV) and vaccinia virus (VACV) infection.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040812 Ensembl Gene Model | MGI Sequence Detail 51711 C57BL/6J ±  kb
transcript ENSMUST00000111481 Ensembl | MGI Sequence Detail 3448 Not Applicable  
polypeptide ENSMUSP00000107106 Ensembl | MGI Sequence Detail 862 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 13
    Primer pair 2

    Microarray probesets 1
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 5
    Phenotypes 20
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:343289 Ho KH, et al., Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory