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Zfp384 Gene Detail
Summary
  • Symbol
    Zfp384
  • Name
    zinc finger protein 384
  • Synonyms
    C130073D16Rik, Ciz, Nmp4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2443203
    NCBI Gene: 269800
  • Alliance
    genome feature page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124986108-125014833 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 59.17 cM, cytoband F1
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    587 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2443203
 protein coding gene Chr6:124985980-125014833 (+)
129S1/SvImJ ENSMUSG00200051013
 protein coding gene Chr6:122047333-122076910 (+)
A/J ENSMUSG00195043993
 protein coding gene Chr6:121493414-121523330 (+)
AKR/J ENSMUSG00220027420
 protein coding gene Chr6:120355007-120384922 (+)
BALB/cJ ENSMUSG00180039836
 protein coding gene Chr6:121832062-121861975 (+)
C3H/HeJ ENSMUSG00175041154
 protein coding gene Chr6:121493877-121523781 (+)
C57BL/6NJ ENSMUSG00215044935
 protein coding gene Chr6:121811070-121840659 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028865
 protein coding gene Chr6:120695652-120725901 (+)
CAST/EiJ ENSTCUG00005047115
 protein coding gene Chr6:121676906-121706826 (+)
CBA/J ENSMUSG00210040348
 protein coding gene Chr6:121532474-121562389 (+)
DBA/2J ENSMUSG00185039871
 protein coding gene Chr6:122232082-122261998 (+)
FVB/NJ ENSMUSG00205029488
 protein coding gene Chr6:120946859-120976777 (+)
JF1/MsJ ENSUMUG00000028459
 protein coding gene Chr6:120640894-120670336 (+)
LP/J ENSMUSG00230043601
 protein coding gene Chr6:123428962-123458876 (+)
NOD/ShiLtJ ENSMUSG00190049570
 protein coding gene Chr6:121203658-121233573 (+)
NZO/HlLtJ ENSMUSG00225015879
 protein coding gene Chr6:125459019-125488806 (+)
PWK/PhJ ENSLUMG00010048089
 protein coding gene Chr6:119908986-119938415 (+)
SPRET/EiJ ENSMSPG00010032477
 protein coding gene Chr6:122758965-122789370 (+)
WSB/EiJ ENSIUOG00005038141
 protein coding gene Chr6:121917608-121947396 (+)



Homology
more
  • Human Ortholog
    ZNF384, zinc finger protein 384
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF384, zinc finger protein 384
  • Synonyms
    CAGH1, CAGH1A, CIZ, ERDA2, NMP4, NP, TNRC1
  • Links
    NCBI Gene ID: 171017
    UniProt: Q8TF68

  • Chr Location
    chr12:6666477-6689572 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous mice are small and males have a small testis. Some males develop infertility and exhibit variable degrees of spermatogenic cell degeneration within the seminiferous tubules and increased apoptosis of spermatogenic cells.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    621
  • Tissues
    15
  • cDNA Data
    38
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000038346 Ensembl Gene Model | MGI Sequence Detail 28726 C57BL/6J ±  kb
    transcript ENSMUST00000112427 Ensembl | MGI Sequence Detail 3072 Not Applicable  
    polypeptide ENSMUSP00000108046 Ensembl | MGI Sequence Detail 584 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      13 Sequences
    • InterPro Domains
      IPR036236 Zinc finger C2H2 superfamily
      IPR013087 Zinc finger C2H2-type
      IPR050331 Zinc finger PRDM4/PRDM1/PRDM14-like
      IPR050758 Zinc finger protein, C2H2-type
    • GlyGen
      E9Q1A5 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 41
      Genomic 1
      cDNA 38
      Primer pair 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1927291, MGI:2141735
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 21
    • Earliest
      J:75532 Alvarez MB, et al., Assignment of Nmp4 to mouse chromosome 6 band F1 flanked by D6Mit134 and D6Mit255 using radiation hybrid mapping and fluorescence in situ hybridization. Cytogenet Cell Genet. 2001;94(3-4):244-5
    • Latest
      J:387340 Tsuyama J, et al., Sustaining microglial reparative function enhances stroke recovery. Nature. 2026 May 13;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory