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Eml6 Gene Detail
Summary
  • Symbol
    Eml6
  • Name
    echinoderm microtubule associated protein like 6
  • Synonyms
    2900083P10Rik, C230094A16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442895
    NCBI Gene: 237711
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:29693048-29976033 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 11, 16.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    7684 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442895
protein coding gene Chr11:29693044-29976044 (-)
129S1/SvImJ ENSMUSG00200009668
protein coding gene Chr11:26726287-27008489 (-)
A/J ENSMUSG00195013420
protein coding gene Chr11:26617104-26899058 (-)
AKR/J ENSMUSG00220007687
protein coding gene Chr11:26827745-27109729 (-)
BALB/cJ ENSMUSG00180007434
protein coding gene Chr11:26637850-26929355 (-)
C3H/HeJ ENSMUSG00175016453
protein coding gene Chr11:26644743-26929752 (-)
C57BL/6NJ ENSMUSG00215009080
protein coding gene Chr11:26597508-26879729 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016162
protein coding gene Chr11:25365509-25639437 (-)
CAST/EiJ ENSTCUG00005027117
protein coding gene Chr11:26486990-26785783 (-)
CBA/J ENSMUSG00210009877
protein coding gene Chr11:26602488-26884898 (-)
DBA/2J ENSMUSG00185018793
protein coding gene Chr11:26703227-26985182 (-)
FVB/NJ ENSMUSG00205020567
protein coding gene Chr11:26692772-26975923 (-)
JF1/MsJ ENSUMUG00000006620
protein coding gene Chr11:26962636-27247742 (-)
LP/J ENSMUSG00230014445
protein coding gene Chr11:27858987-28147696 (-)
NOD/ShiLtJ ENSMUSG00190023139
protein coding gene Chr11:26835105-27117082 (-)
NZO/HlLtJ ENSMUSG00225021285
protein coding gene Chr11:29791323-30073481 (-)
PWK/PhJ ENSLUMG00010017182
protein coding gene Chr11:26609214-26899120 (-)
SPRET/EiJ ENSMSPG00010018885
protein coding gene Chr11:26916265-27242567 (-)
WSB/EiJ ENSIUOG00005012480
protein coding gene Chr11:26705711-26994356 (-)



Homology
more
  • Human Ortholog
    EML6, EMAP like 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EML6, EMAP like 6
  • Links
    NCBI Gene ID: 400954
    UniProt: Q6ZMW3

  • Chr Location
    2p16.1; chr2:54723499-54972025 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000044072 Ensembl Gene Model | MGI Sequence Detail 282986 C57BL/6J ±  kb
transcript ENSMUST00000058902 Ensembl | MGI Sequence Detail 8083 Not Applicable  
polypeptide ENSMUSP00000051080 Ensembl | MGI Sequence Detail 1958 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000007061 echinoderm microtubule-associated protein-like 6
  • InterPro Domains
    IPR055439 EML-like, first beta-propeller domain
    IPR055442 EML-like, second beta-propeller domain
    IPR005108 HELP motif
    IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    IPR050630 WD repeat Echinoderm Microtubule-associated Protein-like
  • GlyGen
    Q5SQM0 2 sites, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGI:1920361
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory