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Fam221a Gene Detail
Summary
  • Symbol
    Fam221a
  • Name
    family with sequence similarity 221, member A
  • Synonyms
    D330028D13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442161
    NCBI Gene: 231946
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:49344673-49367473 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 23.87 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    215 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442161
 protein coding gene Chr6:49343855-49367473 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030724
 protein coding gene Chr6:48385116-48407717 (+)
A/J MGP_AJ_G0030695
 protein coding gene Chr6:46173408-46197492 (+)
AKR/J MGP_AKRJ_G0030620
 protein coding gene Chr6:47806909-47828364 (+)
BALB/cJ MGP_BALBcJ_G0030705
 protein coding gene Chr6:46522167-46542047 (+)
C3H/HeJ MGP_C3HHeJ_G0030418
 protein coding gene Chr6:47816337-47837613 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031160
 protein coding gene Chr6:49524321-49547157 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028367
 protein coding gene Chr6:43772686-43794040 (+)
CAST/EiJ MGP_CASTEiJ_G0029822
 protein coding gene Chr6:47526977-47550053 (+)
CBA/J MGP_CBAJ_G0030393
 protein coding gene Chr6:51589618-51612267 (+)
DBA/2J MGP_DBA2J_G0030542
 protein coding gene Chr6:46086415-46106461 (+)
FVB/NJ MGP_FVBNJ_G0030494
 protein coding gene Chr6:45722756-45745963 (+)
LP/J MGP_LPJ_G0030627
 protein coding gene Chr6:48352365-48379188 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030528
 protein coding gene Chr6:54324012-54359271 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031189
 protein coding gene Chr6:47686020-47710238 (+)
PWK/PhJ MGP_PWKPhJ_G0029534
 protein coding gene Chr6:45634996-45656537 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029370
 protein coding gene Chr6:47010922-47035834 (+)
WSB/EiJ MGP_WSBEiJ_G0029899
 protein coding gene Chr6:47666733-47690256 (+)



Homology
more
  • Human Ortholog
    FAM221A, family with sequence similarity 221 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM221A, family with sequence similarity 221 member A
  • Synonyms
    C7orf46
  • Links
    NCBI Gene ID: 340277
    neXtProt AC: NX_A4D161
    UniProt: A4D161

  • Chr Location
    7p15.3; chr7:23680130-23703249 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047115 Ensembl Gene Model | MGI Sequence Detail 22801 C57BL/6J ±  kb
    transcript ENSMUST00000060561 Ensembl | MGI Sequence Detail 2730 Not Applicable  
    polypeptide ENSMUSP00000050237 Ensembl | MGI Sequence Detail 301 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 3
    References
    more
    • Summaries
      All 21
      Phenotypes 3
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory