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Irf2bp1 Gene Detail
Summary
  • Symbol
    Irf2bp1
  • Name
    interferon regulatory factor 2 binding protein 1
  • Synonyms
    6330414O09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442159
    NCBI Gene: 272359
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:18737983-18740688 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 9.46 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    90 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442159
 protein coding gene Chr7:18737969-18740702 (+)
129S1/SvImJ ENSMUSG00200038970
 protein coding gene Chr7:11927452-11930187 (+)
A/J ENSMUSG00195048963
 protein coding gene Chr7:12374270-12377005 (+)
AKR/J ENSMUSG00220024987
 protein coding gene Chr7:10707076-10709809 (+)
BALB/cJ ENSMUSG00180051511
 protein coding gene Chr7:12230622-12233358 (+)
C3H/HeJ ENSMUSG00175050784
 protein coding gene Chr7:12810039-12812774 (+)
C57BL/6NJ ENSMUSG00215054344
 protein coding gene Chr7:11470244-11472978 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029265
 protein coding gene Chr7:18289946-18292682 (+)
CAST/EiJ ENSTCUG00005048103
 protein coding gene Chr7:12838511-12841245 (+)
CBA/J ENSMUSG00210051283
 protein coding gene Chr7:12036740-12039475 (+)
DBA/2J ENSMUSG00185051860
 protein coding gene Chr7:15483610-15486345 (+)
FVB/NJ ENSMUSG00205049858
 protein coding gene Chr7:12426934-12429667 (+)
JF1/MsJ ENSUMUG00000019962
 protein coding gene Chr7:18794607-18797342 (+)
LP/J ENSMUSG00230045855
 protein coding gene Chr7:19769011-19773030 (+)
NOD/ShiLtJ ENSMUSG00190048868
 protein coding gene Chr7:8692995-8695730 (+)
NZO/HlLtJ ENSMUSG00225052632
 protein coding gene Chr7:17063334-17066069 (+)
PWK/PhJ ENSLUMG00010040404
 protein coding gene Chr7:1641439-1644175 (+)
SPRET/EiJ ENSMSPG00010050853
 protein coding gene Chr7:11768983-11771693 (+)
WSB/EiJ ENSIUOG00005050255
 protein coding gene Chr7:19834230-19836965 (-)



Homology
more
  • Human Ortholog
    IRF2BP1, interferon regulatory factor 2 binding protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IRF2BP1, interferon regulatory factor 2 binding protein 1
  • Links
    NCBI Gene ID: 26145
    UniProt: Q8IU81

  • Chr Location
    19q13.32; chr19:45883608-45886141 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    598
  • Tissues
    1
  • cDNA Data
    87
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 272359 NCBI Gene Model | MGI Sequence Detail 2706 C57BL/6J ±  kb
transcript NM_178757 RefSeq | MGI Sequence Detail 2706 C57BL/6  
polypeptide Q8R3Y8 UniProt | EBI | MGI Sequence Detail 584 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000009103 interferon regulatory factor 2-binding protein 1
    (term hierarchy)
  • EC
    2.3.2.27
  • InterPro Domains
    IPR044882 Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily
    IPR057414 Interferon regulatory factor 2-binding protein 1/2-like, C3HC4 zinc finger domain
    IPR022750 Interferon regulatory factor 2-binding protein 1/2-like, zinc finger
    IPR058682 IRF-2BP1/2-like, middle domain
  • GlyGen
    Q8R3Y8 2 sites
Molecular
Reagents
less
  • All nucleic 87
    cDNA 87

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:389587 Buchse T, et al., CIN85 interacting proteins in B cells-specific role for SHIP-1. Mol Cell Proteomics. 2011 Oct;10(10):M110.006239
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory