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Gpr82 Gene Detail
Summary
  • Symbol
    Gpr82
  • Name
    G protein-coupled receptor 82
  • Feature Type
    protein coding gene
  • IDs
    MGI:2441734
    NCBI Gene: 319200
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:13527602-13533672 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 8.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    206 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2441734
 protein coding gene ChrX:13512373-13533672 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035575
 protein coding gene ChrX:8523499-8531001 (+)
A/J MGP_AJ_G0035553
 protein coding gene ChrX:8615012-8620913 (+)
AKR/J MGP_AKRJ_G0035485
 protein coding gene ChrX:8896876-8902836 (+)
BALB/cJ MGP_BALBcJ_G0035546
 protein coding gene ChrX:8465154-8475160 (+)
C3H/HeJ MGP_C3HHeJ_G0035262
 protein coding gene ChrX:8625107-8631187 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036075
 protein coding gene ChrX:8736613-8743212 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032945
 protein coding gene ChrX:7502585-7508271 (+)
CAST/EiJ MGP_CASTEiJ_G0034554
 protein coding gene ChrX:8374088-8380741 (+)
CBA/J MGP_CBAJ_G0035231
 protein coding gene ChrX:9175110-9181127 (+)
DBA/2J MGP_DBA2J_G0035384
 protein coding gene ChrX:8443554-8449924 (+)
FVB/NJ MGP_FVBNJ_G0035331
 protein coding gene ChrX:8278882-8284790 (+)
LP/J MGP_LPJ_G0035466
 protein coding gene ChrX:8698361-8705421 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035374
 protein coding gene ChrX:9086817-9094193 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036087
 protein coding gene ChrX:8439357-8446008 (+)
PWK/PhJ MGP_PWKPhJ_G0034255
 protein coding gene ChrX:7930703-7937165 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034096
 protein coding gene ChrX:8537995-8546392 (+)
WSB/EiJ MGP_WSBEiJ_G0034690
 protein coding gene ChrX:8475786-8483049 (+)



Homology
more
  • Human Ortholog
    GPR82, G protein-coupled receptor 82
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPR82, G protein-coupled receptor 82
  • Links
    NCBI Gene ID: 27197
    UniProt: Q96P67

  • Chr Location
    Xp11.4; chrX:41724181-41730130 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 2 alleles in 2 genetic backgrounds
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit reduced body weight and body fat content, lower food intake, decreased serum triacylglyceride levels, and improved glucose tolerance. Mice homozygous for another allele display a normal phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    755
  • Tissues
    49
  • cDNA Data
    4
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000047678 Ensembl Gene Model | MGI Sequence Detail 6071 C57BL/6J ±  kb
    transcript ENSMUST00000053659 Ensembl | MGI Sequence Detail 2497 Not Applicable  
    polypeptide ENSMUSP00000062535 Ensembl | MGI Sequence Detail 328 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 4
      Primer pair 1
      Other 1

      Microarray probesets 1
    References
    more
    • Summaries
      All 16
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 3
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:301613 Engel KM, et al., Reduced food intake and body weight in mice deficient for the G protein-coupled receptor GPR82. PLoS One. 2011;6(12):e29400
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory