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Plekha6 Gene Detail
Summary
  • Symbol
    Plekha6
  • Name
    pleckstrin homology domain containing, family A member 6
  • Synonyms
    Pepp3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388662
    NCBI Gene: 240753
  • Alliance
    gene page
  • Transcription Start Sites
    16 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:133091948-133231173 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 57.91 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    819 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388662
 protein coding gene Chr1:133089770-133231173 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016481
 protein coding gene Chr1:136778456-136838254 (+)
A/J MGP_AJ_G0016464
 protein coding gene Chr1:131702367-131761245 (+)
AKR/J MGP_AKRJ_G0016429
 protein coding gene Chr1:135586198-135647381 (+)
BALB/cJ MGP_BALBcJ_G0016424
 protein coding gene Chr1:131967700-132091872 (+)
C3H/HeJ MGP_C3HHeJ_G0016250
 protein coding gene Chr1:135720427-135780254 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016885
 protein coding gene Chr1:141844387-141905893 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014596
 protein coding gene Chr1:124856477-124913507 (+)
CAST/EiJ MGP_CASTEiJ_G0015830
 protein coding gene Chr1:134748325-134807810 (+)
CBA/J MGP_CBAJ_G0016222
 protein coding gene Chr1:146671057-146728181 (+)
DBA/2J MGP_DBA2J_G0016329
 protein coding gene Chr1:130672945-130730292 (+)
FVB/NJ MGP_FVBNJ_G0016328
 protein coding gene Chr1:129314092-129371328 (+)
LP/J MGP_LPJ_G0016400
 protein coding gene Chr1:138089928-138147751 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016353
 protein coding gene Chr1:152452188-152511693 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016921
 protein coding gene Chr1:135327049-135385358 (+)
PWK/PhJ MGP_PWKPhJ_G0015616
 protein coding gene Chr1:129677681-129736360 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015403
 protein coding gene Chr1:134203021-134345556 (+)
WSB/EiJ MGP_WSBEiJ_G0015892
 protein coding gene Chr1:135336456-135395846 (+)



Homology
more
  • Human Ortholog
    PLEKHA6, pleckstrin homology domain containing A6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLEKHA6, pleckstrin homology domain containing A6
  • Synonyms
    PEPP3, PEPP-3
  • Links
    NCBI Gene ID: 22874
    neXtProt AC: NX_Q9Y2H5
    UniProt: Q9Y2H5

  • Chr Location
    1q32.1; chr1:204218853-204378168 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    77
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041757 Ensembl Gene Model | MGI Sequence Detail 139226 C57BL/6J ±  kb
transcript ENSMUST00000038295 Ensembl | MGI Sequence Detail 7388 Not Applicable  
polypeptide ENSMUSP00000048214 Ensembl | MGI Sequence Detail 1173 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 78
    cDNA 77
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2138495
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:256807 Ushiki A, et al., Long-Range Control of Renin Gene Expression in Tsukuba Hypertensive Mice. PLoS One. 2016;11(11):e0166974
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory