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Acsf2 Gene Detail
Summary
  • Symbol
    Acsf2
  • Name
    acyl-CoA synthetase family member 2
  • Synonyms
    MGC:25878
  • Feature Type
    protein coding gene
  • IDs
    MGI:2388287
    NCBI Gene: 264895
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:94447928-94492697 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 58.90 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    451 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2388287
 protein coding gene Chr11:94447928-94492822 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018961
 protein coding gene Chr11:96662918-96717592 (-)
A/J MGP_AJ_G0018929
 protein coding gene Chr11:92789786-92836926 (-)
AKR/J MGP_AKRJ_G0018899
 protein coding gene Chr11:95673881-95728515 (-)
BALB/cJ MGP_BALBcJ_G0018902
 protein coding gene Chr11:93239963-93287661 (-)
C3H/HeJ MGP_C3HHeJ_G0018716
 protein coding gene Chr11:95759145-95808946 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019354
 protein coding gene Chr11:99668859-99724021 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016985
 protein coding gene Chr11:90284672-90327203 (-)
CAST/EiJ MGP_CASTEiJ_G0018271
 protein coding gene Chr11:96478624-96529998 (-)
CBA/J MGP_CBAJ_G0018687
 protein coding gene Chr11:103800674-103872947 (-)
DBA/2J MGP_DBA2J_G0018795
 protein coding gene Chr11:92366988-92414382 (-)
FVB/NJ MGP_FVBNJ_G0018784
 protein coding gene Chr11:91787035-91835519 (-)
LP/J MGP_LPJ_G0018865
 protein coding gene Chr11:97204935-97255467 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018811
 protein coding gene Chr11:103828239-103879301 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0018041
 protein coding gene Chr11:93301888-93353031 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017831
 protein coding gene Chr11:95568259-95628504 (-)
WSB/EiJ MGP_WSBEiJ_G0018320
 protein coding gene Chr11:95789713-95837500 (-)



Homology
more
  • Human Ortholog
    ACSF2, acyl-CoA synthetase family member 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACSF2, acyl-CoA synthetase family member 2
  • Synonyms
    ACSMW, AVYV493
  • Links
    NCBI Gene ID: 80221
    neXtProt AC: NX_Q96CM8
    UniProt: Q96CM8

  • Chr Location
    17q21.33; chr17:50426158-50474845 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation has no notable phenotype in any parameter tested.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    740
  • Tissues
    26
  • cDNA Data
    26
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000076435 Ensembl Gene Model | MGI Sequence Detail 44770 C57BL/6J ±  kb
transcript ENSMUST00000103164 Ensembl | MGI Sequence Detail 3154 Not Applicable  
polypeptide ENSMUSP00000099453 Ensembl | MGI Sequence Detail 615 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    Genomic 1
    cDNA 26

    Microarray probesets 3
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 6
    Phenotypes 17
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:246066 Sundberg JP, et al., Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. PLoS One. 2017;12(7):e0180682
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory