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Tg(CAG-Hsp70-1)1Whd
Transgene Detail
Summary
Symbol: Tg(CAG-Hsp70-1)1Whd
Name: transgene insertion 1, Wolfgang H Dillmann
MGI ID: MGI:2385686
Synonyms: HSP72Tg, Tg(Actb-Hsp70-1)1Whd, Tg(CAG-Hsp70-1)1Whd
Transgene: Tg(CAG-Hsp70-1)1Whd  Location: unknown  
Alliance: Tg(CAG-Hsp70-1)1Whd page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CAG-Hsp70-1)1Whd expresses 1 gene
 
Mutation detailsThe rat Hsp70-1 gene under the control of human CMV immediate early enhancer and chicken beta-actin promoter sequence (including intron 1) was used as the transgene. Overexpression of the rat transgene was verified by Western blot analysis of heart and Northern blot analysis of cardiac and skeletal tissue from transgenic animals. (J:70884)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:70884 Marber MS, et al., Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J Clin Invest. 1995 Apr;95(4):1446-56
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory