About   Help   FAQ
Tgif2lx1 Gene Detail
Summary
  • Symbol
    Tgif2lx1
  • Name
    TGFB-induced factor homeobox 2-like, X-linked 1
  • Synonyms
    Tex1, Tgif2lx, Tgifx1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387796
    NCBI Gene: 245583
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    ChrX:117389405-117390426 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 49.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    16 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387796
 protein coding gene ChrX:117389405-117390434 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0036024
 protein coding gene ChrX:114992691-114993751 (+)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0036016
 protein coding gene ChrX:113501000-113502060 (-)
C3H/HeJ MGP_C3HHeJ_G0035721
 protein coding gene ChrX:115639673-115640733 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0033366
 protein coding gene ChrX:111222645-111223237 (+)
CAST/EiJ MGP_CASTEiJ_G0035009
 protein coding gene ChrX:99348113-99349142 (+)
CBA/J MGP_CBAJ_G0035697
 protein coding gene ChrX:122519475-122520535 (-)
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0035792
 protein coding gene ChrX:113590542-113591571 (+)
LP/J MGP_LPJ_G0035942
 protein coding gene ChrX:116215078-116216107 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0036567
 protein coding gene ChrX:114843050-114844079 (-)
PWK/PhJ MGP_PWKPhJ_G0034701
 protein coding gene ChrX:96728415-96729475 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    TGIF2LX, TGFB induced factor homeobox 2 like X-linked
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TGIF2LX, TGFB induced factor homeobox 2 like X-linked
  • Synonyms
    TGIFLX
  • Links
    NCBI Gene ID: 90316
    neXtProt AC: NX_Q8IUE1
    UniProt: Q8IUE1

  • Chr Location
    Xq21.31; chrX:89921908-89922883 (+)  GRCh38
  • Human Ortholog
    TGIF2LY, TGFB induced factor homeobox 2 like Y-linked
  • Synonyms
    TGIFLY
  • Links
    NCBI Gene ID: 90655
    neXtProt AC: NX_Q8IUE0
    UniProt: Q8IUE0

  • Chr Location
    Yp11.2; chrY:3579067-3580041 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
Male mice hemizygous for a null allele exhibit normal fecundity.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    789
  • Tissues
    72
  • cDNA Data
    4
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 245583 NCBI Gene Model | MGI Sequence Detail 1022 C57BL/6J ±  kb
transcript NM_153109 RefSeq | MGI Sequence Detail 1036 Not Specified  
polypeptide NP_694749 RefSeq | MGI Sequence Detail 231 Not Specified  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 6
    cDNA 5
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:3712529
References
more
  • Summaries
    All 23
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 1
  • Earliest
    J:73769 Nakamura K, et al., Molecular cloning of a mouse scavenger receptor with C-type lectin (SRCL)(1), a novel member of the scavenger receptor family. Biochim Biophys Acta. 2001 Nov 11;1522(1):53-8
  • Latest
    J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory