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Gipc3 Gene Detail
Summary
  • Symbol
    Gipc3
  • Name
    GIPC PDZ domain containing family, member 3
  • Synonyms
    Ahl5, Gipc3, Rgs19ip3
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387006
    NCBI Gene: 209047
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:81171099-81179100 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 39.72 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    8 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387006
 protein coding gene Chr10:81171096-81179452 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017552
 protein coding gene Chr10:82050271-82055648 (-)
A/J MGP_AJ_G0017530
 protein coding gene Chr10:79141310-79147115 (-)
AKR/J MGP_AKRJ_G0017491
 protein coding gene Chr10:81316396-81321868 (-)
BALB/cJ MGP_BALBcJ_G0017492
 protein coding gene Chr10:79361226-79366920 (-)
C3H/HeJ MGP_C3HHeJ_G0017315
 protein coding gene Chr10:81416860-81422287 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017946
 protein coding gene Chr10:84867320-84872816 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015635
 protein coding gene Chr10:75338183-75344178 (-)
CAST/EiJ MGP_CASTEiJ_G0016882
 protein coding gene Chr10:81644369-81650746 (-)
CBA/J MGP_CBAJ_G0017287
 protein coding gene Chr10:88181343-88188643 (-)
DBA/2J MGP_DBA2J_G0017393
 protein coding gene Chr10:78346480-78351739 (-)
FVB/NJ MGP_FVBNJ_G0017387
 protein coding gene Chr10:77595621-77600502 (-)
LP/J MGP_LPJ_G0017464
 protein coding gene Chr10:82497179-82502858 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017413
 protein coding gene Chr10:90021702-90029123 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017987
 protein coding gene Chr10:81325033-81331477 (-)
PWK/PhJ MGP_PWKPhJ_G0016663
 protein coding gene Chr10:78240042-78245467 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016453
 protein coding gene Chr10:80268641-80273948 (-)
WSB/EiJ MGP_WSBEiJ_G0016942
 protein coding gene Chr10:81355410-81361931 (-)



Homology
more
  • Human Ortholog
    GIPC3, GIPC PDZ domain containing family member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GIPC3, GIPC PDZ domain containing family member 3
  • Synonyms
    C19orf64, DFNB15, DFNB72, DFNB95
  • Links
    NCBI Gene ID: 126326
    neXtProt AC: NX_Q8TF64
    UniProt: Q8TF64

  • Chr Location
    19p13.3; chr19:3585478-3593541 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human GIPC3 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    16
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000034872 Ensembl Gene Model | MGI Sequence Detail 8002 C57BL/6J ±  kb
    transcript ENSMUST00000045102 Ensembl | MGI Sequence Detail 3521 Not Applicable  
    polypeptide ENSMUSP00000049236 Ensembl | MGI Sequence Detail 297 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 2
      Primer pair 1
      Other 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:3514193
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 3
      Phenotypes 16
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:337065 Chatterjee P, et al., GIPC3 couples to MYO6 and PDZ domain proteins, and shapes the hair cell apical region. J Cell Sci. 2023 May 15;136(10)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/09/2024
    MGI 6.23     		The Jackson Laboratory