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Ebf4 Gene Detail
Summary
  • Symbol
    Ebf4
  • Name
    early B cell factor 4
  • Synonyms
    O/E-4, Olf-1/EBF-like 4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385972
    NCBI Gene: 228598
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:130137089-130212401 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 63.21 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    239 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385972
 protein coding gene Chr2:130134832-130212402 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026499
 protein coding gene Chr2:133743872-133829480 (+)
A/J MGP_AJ_G0026463
 protein coding gene Chr2:128334071-128409700 (+)
AKR/J MGP_AKRJ_G0026438
 protein coding gene Chr2:132018920-132108125 (+)
BALB/cJ MGP_BALBcJ_G0026475
 protein coding gene Chr2:128691988-128764875 (+)
C3H/HeJ MGP_C3HHeJ_G0026218
 protein coding gene Chr2:132469419-132543949 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026920
 protein coding gene Chr2:137888890-137968184 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024297
 protein coding gene Chr2:123078739-123152585 (+)
CAST/EiJ MGP_CASTEiJ_G0025679
 protein coding gene Chr2:132719867-132798966 (+)
CBA/J MGP_CBAJ_G0026198
 protein coding gene Chr2:142992187-143069716 (+)
DBA/2J MGP_DBA2J_G0026332
 protein coding gene Chr2:127722591-127796132 (+)
FVB/NJ MGP_FVBNJ_G0026296
 protein coding gene Chr2:126345160-126419449 (+)
LP/J MGP_LPJ_G0026437
 protein coding gene Chr2:134007973-134081186 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026316
 protein coding gene Chr2:146843867-146923621 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026975
 protein coding gene Chr2:131989412-132068675 (+)
PWK/PhJ MGP_PWKPhJ_G0025415
 protein coding gene Chr2:127276670-127350846 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025217
 protein coding gene Chr2:131107076-131187300 (+)
WSB/EiJ MGP_WSBEiJ_G0025753
 protein coding gene Chr2:132916142-132989754 (+)



Homology
more
  • Human Ortholog
    EBF4, EBF family member 4
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EBF4, EBF family member 4
  • Synonyms
    COE4, O/E-4, OE-4
  • Links
    NCBI Gene ID: 57593
    neXtProt AC: NX_Q9BQW3
    UniProt: Q9BQW3

  • Chr Location
    20p13; chr20:2692780-2760108 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    808
  • Tissues
    87
  • cDNA Data
    11
  • Literature Summary
    12
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000053552 Ensembl Gene Model | MGI Sequence Detail 75313 C57BL/6J ±  kb
    transcript ENSMUST00000110288 Ensembl | MGI Sequence Detail 2982 Not Applicable  
    polypeptide ENSMUSP00000105917 Ensembl | MGI Sequence Detail 696 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 12
      Primer pair 2

      Microarray probesets 2
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 12
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:288306 Kuriki M, et al., Transient and lineage-restricted requirement of Ebf3 for sternum ossification. Development. 2020 May 12;147(9):dev186239
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory