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Cybc1 Gene Detail
Summary
  • Symbol
    Cybc1
  • Name
    cytochrome b 245 chaperone 1
  • Synonyms
    BC017643, MGC:28978, MGC:37062, MGC:37382
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384959
    NCBI Gene: 217370
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:121113414-121120135 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 85.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    70 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384959
 protein coding gene Chr11:121113414-121120148 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019543
 protein coding gene Chr11:125759034-125766191 (-)
A/J MGP_AJ_G0019510
 protein coding gene Chr11:120140835-120147567 (-)
AKR/J MGP_AKRJ_G0019480
 protein coding gene Chr11:123782266-123788368 (-)
BALB/cJ MGP_BALBcJ_G0019485
 protein coding gene Chr11:120511276-120518005 (-)
C3H/HeJ MGP_C3HHeJ_G0019291
 protein coding gene Chr11:124106079-124113496 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019934
 protein coding gene Chr11:129573689-129580423 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017559
 protein coding gene Chr11:117125822-117132736 (-)
CAST/EiJ MGP_CASTEiJ_G0018845
 protein coding gene Chr11:125612429-125618535 (-)
CBA/J MGP_CBAJ_G0019262
 protein coding gene Chr11:134607055-134613789 (-)
DBA/2J MGP_DBA2J_G0019375
 protein coding gene Chr11:119511613-119518343 (-)
FVB/NJ MGP_FVBNJ_G0019366
 protein coding gene Chr11:119229803-119236537 (-)
LP/J MGP_LPJ_G0019446
 protein coding gene Chr11:126037804-126044532 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019399
 protein coding gene Chr11:133421727-133428459 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019973
 protein coding gene Chr11:124462659-124469393 (-)
PWK/PhJ MGP_PWKPhJ_G0018612
 protein coding gene Chr11:120954827-120961765 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018403
 protein coding gene Chr11:124219243-124225953 (-)
WSB/EiJ MGP_WSBEiJ_G0018898
 protein coding gene Chr11:124435226-124441936 (-)



Homology
more
  • Human Ortholog
    CYBC1, cytochrome b-245 chaperone 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYBC1, cytochrome b-245 chaperone 1
  • Synonyms
    C17orf62, CGD5, Eros
  • Links
    NCBI Gene ID: 79415
    neXtProt AC: NX_Q9BQA9
    UniProt: Q9BQA9

  • Chr Location
    17q25.3; chr17:82440912-82450829 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CYBC1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    17
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 217370 NCBI Gene Model | MGI Sequence Detail 6722 C57BL/6J ±  kb
    transcript NM_144832 RefSeq | MGI Sequence Detail 2483 C57BL/6  
    polypeptide Q3TYS2 UniProt | EBI | MGI Sequence Detail 187 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 18

      Microarray probesets 4
    References
    more
    • Summaries
      All 34
      Gene Ontology 4
      Phenotypes 11
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:333690 Randzavola LO, et al., EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling. Elife. 2022 Nov 24;11
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory