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Clca3b Gene Detail
Summary
  • Symbol
    Clca3b
  • Name
    chloride channel accessory 3B
  • Synonyms
    Clca4
  • Feature Type
    protein coding gene
  • IDs
    MGI:2181989
    NCBI Gene: 229927
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:144528384-144555063 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 69.14 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    418 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2181989
 protein coding gene Chr3:144528384-144555118 (-)
129S1/SvImJ ENSMUSG00200002059
 protein coding gene Chr3:141388127-141414896 (-)
A/J ENSMUSG00195004096
 protein coding gene Chr3:141534903-141561666 (-)
AKR/J ENSMUSG00220002749
 protein coding gene Chr3:139944139-139970903 (-)
BALB/cJ ENSMUSG00180011310
 protein coding gene Chr3:141405423-141432190 (-)
C3H/HeJ ENSMUSG00175019350
 protein coding gene Chr3:140988943-141015698 (-)
C57BL/6NJ ENSMUSG00215011200
 protein coding gene Chr3:141712332-141739079 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025706
 protein coding gene Chr3:138000584-138020275 (-)
CAST/EiJ ENSTCUG00005028212
 protein coding gene Chr3:142118547-142137549 (-)
CBA/J no annotation
DBA/2J ENSMUSG00185023143
 protein coding gene Chr3:142265249-142291730 (-)
FVB/NJ no annotation
JF1/MsJ ENSUMUG00000003629
 protein coding gene Chr3:141072353-141091756 (-)
LP/J ENSMUSG00230015643
 protein coding gene Chr3:144174633-144201392 (-)
NOD/ShiLtJ ENSMUSG00190004335
 protein coding gene Chr3:142625336-142652097 (-)
NZO/HlLtJ ENSMUSG00225001874
 protein coding gene Chr3:146691713-146718475 (-)
PWK/PhJ ENSLUMG00010019848
 protein coding gene Chr3:140980154-141005841 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005017577
 protein coding gene Chr3:141722422-141751731 (-)



Homology
more
  • Human Ortholog
    CLCA3P, chloride channel accessory 3, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CLCA3P, chloride channel accessory 3, pseudogene
  • Synonyms
    CLCA3
  • Links
    NCBI Gene ID: 9629

  • Chr Location
    1p22.3; chr1:86634273-86655376 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    681
  • Tissues
    35
  • cDNA Data
    14
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 229927 NCBI Gene Model | MGI Sequence Detail 26680 C57BL/6J ±  kb
transcript NM_139148 RefSeq | MGI Sequence Detail 3306 C57BL/6  
polypeptide NP_631887 RefSeq | MGI Sequence Detail 1044 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR013642 Calcium-activated chloride channel, N-terminal
    IPR004727 Calcium-activated chloride channel protein, chordata
    IPR051266 Calcium-activated chloride channel regulator
    IPR061453 Choice-of-anchor X domain
    IPR036465 von Willebrand factor A-like domain superfamily
    IPR002035 von Willebrand factor, type A
  • GlyGen
    E9PUL3 19 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 19
    cDNA 14
    Primer pair 4
    Other 1

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:70677 Cook SA, et al., Mouse paracentric inversion In(3)55Rk mutates the urate oxidase gene. Cytogenet Cell Genet. 2001;93(1-2):77-82
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory