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Klf17 Gene Detail
Summary
  • Symbol
    Klf17
  • Name
    Kruppel-like transcription factor 17
  • Synonyms
    7420700M05Rik, D4Ertd561e, Zfp393
  • Feature Type
    protein coding gene
  • IDs
    MGI:2181068
    NCBI Gene: 75753
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:117615033-117622845 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 53.46 cM, cytoband D1
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    374 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2181068
 protein coding gene Chr4:117613856-117622863 (-)
129S1/SvImJ ENSMUSG00200046515
 protein coding gene Chr4:111513598-111521680 (-)
A/J ENSMUSG00195028512
 protein coding gene Chr4:112760199-112768318 (-)
AKR/J ENSMUSG00220020797
 protein coding gene Chr4:112115241-112123365 (-)
BALB/cJ ENSMUSG00180040606
 protein coding gene Chr4:110827393-110835530 (-)
C3H/HeJ ENSMUSG00175033947
 protein coding gene Chr4:111841654-111849791 (-)
C57BL/6NJ ENSMUSG00215030377
 protein coding gene Chr4:112939606-112947685 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026361
 protein coding gene Chr4:108198917-108207545 (-)
CAST/EiJ ENSTCUG00005021864
 protein coding gene Chr4:111627102-111635226 (-)
CBA/J ENSMUSG00210053082
 protein coding gene Chr4:111455334-111463469 (-)
DBA/2J ENSMUSG00185043780
 protein coding gene Chr4:112985769-112993887 (-)
FVB/NJ ENSMUSG00205041996
 protein coding gene Chr4:110924785-110932923 (-)
JF1/MsJ ENSUMUG00000014785
 protein coding gene Chr4:112894820-112902920 (-)
LP/J ENSMUSG00230042257
 protein coding gene Chr4:116329181-116337262 (-)
NOD/ShiLtJ ENSMUSG00190029927
 protein coding gene Chr4:110829338-110837462 (-)
NZO/HlLtJ ENSMUSG00225009063
 protein coding gene Chr4:121811885-121819966 (-)
PWK/PhJ ENSLUMG00010042911
 protein coding gene Chr4:110293127-110301230 (-)
SPRET/EiJ ENSMSPG00010035196
 protein coding gene Chr4:112393273-112400688 (-)
WSB/EiJ ENSIUOG00005039014
 protein coding gene Chr4:111147488-111155606 (-)



Homology
more
  • Human Ortholog
    KLF17, KLF transcription factor 17
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLF17, KLF transcription factor 17
  • Synonyms
    Zfp393, ZLF393, ZNF393
  • Links
    NCBI Gene ID: 128209
    UniProt: Q5JT82

  • Chr Location
    1p34.1; chr1:44043927-44135140 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    671
  • Tissues
    48
  • cDNA Data
    180
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048626 Ensembl Gene Model | MGI Sequence Detail 7813 C57BL/6J ±  kb
transcript ENSMUST00000062747 Ensembl | MGI Sequence Detail 2400 Not Applicable  
polypeptide ENSMUSP00000052316 Ensembl | MGI Sequence Detail 341 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 185
    cDNA 180
    Primer pair 5

    Microarray probesets 6
Other
Accession IDs
less
MGI:1261762, MGI:1923003, MGI:2138777, MGI:2140488, MGI:2140697
References
more
  • Summaries
    All 56
    Developmental Gene Expression 6
    Gene Ontology 6
    Phenotypes 16
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:381193 Hu Y, et al., Nascent transcriptome of embryonic genome activation reveals a regulatory axis linking transcriptional priming to early lineage specification in mouse embryos. Nucleic Acids Res. 2026 Feb 24;54(5)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory