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Rhobtb2 Gene Detail
Summary
  • Symbol
    Rhobtb2
  • Name
    Rho-related BTB domain containing 2
  • Synonyms
    Dbc2, E130206H14Rik, mKIAA0717
  • Feature Type
    protein coding gene
  • IDs
    MGI:2180557
    NCBI Gene: 246710
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:70022439-70043085 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 36.10 cM, cytoband D1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    130 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2180557
 protein coding gene Chr14:70022439-70062296 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021526
 protein coding gene Chr14:64377027-64398781 (-)
A/J MGP_AJ_G0021485
 protein coding gene Chr14:63041069-63062023 (-)
AKR/J MGP_AKRJ_G0021461
 protein coding gene Chr14:64931203-64951773 (-)
BALB/cJ MGP_BALBcJ_G0021491
 protein coding gene Chr14:62799883-62820962 (-)
C3H/HeJ MGP_C3HHeJ_G0021268
 protein coding gene Chr14:64649460-64669767 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021930
 protein coding gene Chr14:67271229-67298891 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019470
 protein coding gene Chr14:60875516-60896923 (-)
CAST/EiJ MGP_CASTEiJ_G0020785
 protein coding gene Chr14:61206045-61231954 (-)
CBA/J MGP_CBAJ_G0021235
 protein coding gene Chr14:69384776-69405334 (-)
DBA/2J MGP_DBA2J_G0021358
 protein coding gene Chr14:62422554-62443504 (-)
FVB/NJ MGP_FVBNJ_G0021337
 protein coding gene Chr14:61848650-61871336 (-)
LP/J MGP_LPJ_G0021429
 protein coding gene Chr14:65635274-65656781 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021366
 protein coding gene Chr14:68318079-68339119 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021954
 protein coding gene Chr14:64190040-64212026 (-)
PWK/PhJ MGP_PWKPhJ_G0020529
 protein coding gene Chr14:59175431-59198970 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020362
 protein coding gene Chr14:60112291-60132913 (-)
WSB/EiJ MGP_WSBEiJ_G0020838
 protein coding gene Chr14:64490029-64513241 (-)



Homology
more
  • Human Ortholog
    RHOBTB2, Rho related BTB domain containing 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RHOBTB2, Rho related BTB domain containing 2
  • Synonyms
    DBC2, DEE64, EIEE64, p83
  • Links
    NCBI Gene ID: 23221
    neXtProt AC: NX_Q9BYZ6
    UniProt: Q9BYZ6

  • Chr Location
    8p21.3; chr8:22950813-23020509 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human RHOBTB2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    769
  • Tissues
    37
  • cDNA Data
    64
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022075 Ensembl Gene Model | MGI Sequence Detail 20647 C57BL/6J ±  kb
transcript ENSMUST00000022665 Ensembl | MGI Sequence Detail 5322 Not Applicable  
polypeptide ENSMUSP00000022665 Ensembl | MGI Sequence Detail 728 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 68
    cDNA 66
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925981
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:226884 Lutz J, et al., Expression analysis of mouse Rhobtb3 using a LacZ reporter and preliminary characterization of a knockout strain. Histochem Cell Biol. 2014 Nov;142(5):511-28
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory