About   Help   FAQ
Zfp358 Gene Detail
Summary
  • Symbol
    Zfp358
  • Name
    zinc finger protein 358
  • Synonyms
    Zfend
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153740
    NCBI Gene: 140482
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:3543138-3547208 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 1.92 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    130 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153740
 protein coding gene Chr8:3543138-3547208 (+)
129S1/SvImJ ENSMUSG00200011031
 protein coding gene Chr8:357314-361427 (+)
A/J ENSMUSG00195009688
 protein coding gene Chr8:766637-770707 (+)
AKR/J ENSMUSG00220010106
 protein coding gene Chr8:493168-497238 (+)
BALB/cJ ENSMUSG00180004399
 protein coding gene Chr8:417223-421293 (+)
C3H/HeJ ENSMUSG00175007324
 protein coding gene Chr8:531745-535815 (+)
C57BL/6NJ ENSMUSG00215008490
 protein coding gene Chr8:446107-450177 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030770
 protein coding gene Chr8:359481-363564 (+)
CAST/EiJ ENSTCUG00005019496
 protein coding gene Chr8:507081-511174 (+)
CBA/J ENSMUSG00210010341
 protein coding gene Chr8:409316-413386 (+)
DBA/2J ENSMUSG00185003321
 protein coding gene Chr8:545360-549430 (+)
FVB/NJ ENSMUSG00205004948
 protein coding gene Chr8:479168-483238 (+)
JF1/MsJ ENSUMUG00000040417
 protein coding gene Chr8:493901-498014 (+)
LP/J ENSMUSG00230005770
 protein coding gene Chr8:2714945-2719015 (+)
NOD/ShiLtJ ENSMUSG00190010142
 protein coding gene Chr8:519383-523453 (+)
NZO/HlLtJ ENSMUSG00225016493
 protein coding gene Chr8:10581978-10586048 (+)
PWK/PhJ ENSLUMG00010009263
 protein coding gene Chr8:451149-455262 (+)
SPRET/EiJ ENSMSPG00010015693
 protein coding gene Chr8:424870-428942 (+)
WSB/EiJ ENSIUOG00005004277
 protein coding gene Chr8:455547-459617 (+)



Homology
more
  • Human Ortholog
    ZNF358, zinc finger protein 358
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF358, zinc finger protein 358
  • Synonyms
    ZFEND
  • Links
    NCBI Gene ID: 140467
    UniProt: Q9NW07

  • Chr Location
    19p13.2; chr19:7513880-7521027 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    123
  • cDNA Data
    58
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 140482 NCBI Gene Model | MGI Sequence Detail 4071 C57BL/6J ±  kb
transcript NM_080461 RefSeq | MGI Sequence Detail 1999 ZRU/MplStud  
polypeptide NP_536709 RefSeq | MGI Sequence Detail 571 ZRU/MplStud  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR050717 C2H2-type Zinc-Finger Transcription Regulators
    IPR050329 GLI C2H2-type zinc-finger
    IPR036236 Zinc finger C2H2 superfamily
    IPR013087 Zinc finger C2H2-type
Molecular
Reagents
less
  • All nucleic 59
    cDNA 58
    Other 1

    Microarray probesets 5
References
more
  • Summaries
    All 29
    Developmental Gene Expression 5
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:72872 Bain G, et al., ES cell neural differentiation reveals a substantial number of novel ESTs. Funct Integr Genomics. 2000 Sep;1(2):127-139
  • Latest
    J:190636 Wiese CB, et al., A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory