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Ube2j2 Gene Detail
Summary
  • Symbol
    Ube2j2
  • Name
    ubiquitin-conjugating enzyme E2J 2
  • Synonyms
    1200007B18Rik, 2400008G19Rik, 5730472G04Rik, Ubc6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2153608
    NCBI Gene: 140499
  • Alliance
    genome feature page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:156028288-156044061 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 87.66 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    744 from dbSNP Build 142
  • Strain Annotations
    26
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2153608
 protein coding gene Chr4:156028270-156044061 (+)
129S1/SvImJ ENSMUSG00200019578
 protein coding gene Chr4:147075607-147075711 (+)
129S1/SvImJ ENSMUSGG00200054872
 protein coding gene Chr4:147078094-147083952 (+)
A/J ENSMUSG00195018861
 protein coding gene Chr4:148741746-148741850 (+)
A/J ENSMUSGG00195054997
 protein coding gene Chr4:148744233-148750091 (+)
AKR/J ENSMUSGG00220054634
 protein coding gene Chr4:148319559-148325419 (+)
AKR/J ENSMUSG00220024431
 protein coding gene Chr4:148317072-148317176 (+)
BALB/cJ ENSMUSGG00180055485
 protein coding gene Chr4:146398774-146404632 (+)
BALB/cJ ENSMUSG00180002092
 protein coding gene Chr4:146396287-146396391 (+)
C3H/HeJ ENSMUSGG00175054713
 protein coding gene Chr4:149699396-149705254 (+)
C3H/HeJ ENSMUSG00175015228
 protein coding gene Chr4:149696909-149697013 (+)
C57BL/6NJ ENSMUSG00215017477
 protein coding gene Chr4:148556592-148556696 (+)
C57BL/6NJ ENSMUSGG00215055205
 protein coding gene Chr4:148559082-148564686 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026913
 protein coding gene Chr4:145831894-145848008 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210003884
 protein coding gene Chr4:148355262-148355366 (+)
CBA/J ENSMUSGG00210054722
 protein coding gene Chr4:148357749-148363608 (+)
DBA/2J ENSMUSG00185015489
 protein coding gene Chr4:151912798-151912902 (+)
DBA/2J ENSMUSGG00185057522
 protein coding gene Chr4:151915285-151921143 (+)
FVB/NJ ENSMUSG00205018868
 protein coding gene Chr4:146816644-146816748 (+)
FVB/NJ ENSMUSGG00205054532
 protein coding gene Chr4:146819132-146824980 (+)
JF1/MsJ no annotation
LP/J ENSMUSG00230023481
 protein coding gene Chr4:158664468-158664572 (+)
LP/J ENSMUSGG00230055756
 protein coding gene Chr4:158666958-158672562 (+)
NOD/ShiLtJ ENSMUSG00190003928
 protein coding gene Chr4:148020440-148020544 (+)
NOD/ShiLtJ ENSMUSGG00190054663
 protein coding gene Chr4:148022928-148028775 (+)
NZO/HlLtJ ENSMUSG00225023942
 protein coding gene Chr4:162630078-162645802 (+)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010020008
 protein coding gene Chr4:149134086-149149864 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    UBE2J2, ubiquitin conjugating enzyme E2 J2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UBE2J2, ubiquitin conjugating enzyme E2 J2
  • Synonyms
    NCUBE-2, NCUBE2, PRO2121, UBC6
  • Links
    NCBI Gene ID: 118424
    UniProt: Q8N2K1

  • Chr Location
    1p36.33; chr1:1253907-1274477 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    32 phenotypes from 2 alleles in 2 genetic backgrounds
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null males are infertile and exhibit azoospermia with spermatocytes undergoing meiotic arrest at mid-pachynema.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    107
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000023286 Ensembl Gene Model | MGI Sequence Detail 15774 C57BL/6J ±  kb
    transcript ENSMUST00000105582 Ensembl | MGI Sequence Detail 1394 Not Applicable  
    polypeptide ENSMUSP00000101207 Ensembl | MGI Sequence Detail 271 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 109
      Genomic 1
      cDNA 108

      Microarray probesets 8
    Other
    Accession IDs
    less
    MGI:1914849, MGI:1916985, MGI:1921081, MGI:2145714
    References
    more
    • Summaries
      All 52
      Gene Ontology 10
      Phenotypes 16
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:370390 Yu X, et al., UBE2J2 is essential for the progression of meiosis prophase I during spermatogenesis in mice. iScience. 2025 Aug 15;28(8):112878
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/01/2026
    MGI 6.24     		The Jackson Laboratory