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Firre Gene Detail
Summary
  • Symbol
    Firre
  • Name
    functional intergenic repeating RNA element
  • Synonyms
    5830467J12Rik, 6720401G13Rik
  • Feature Type
    lncRNA gene
  • IDs
    MGI:2147989
    NCBI Gene: 103012
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:49651997-49724198 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 26.53 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    207 from dbSNP Build 142
  • Strain Annotations
    16
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147989
 lncRNA gene ChrX:49644621-49724198 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015777
 unclassified non-coding RNA gene ChrX:45696757-45781912 (-)
A/J MGP_AJ_G0015754
 unclassified non-coding RNA gene ChrX:45565558-45651331 (-)
AKR/J MGP_AKRJ_G0015716
 unclassified non-coding RNA gene ChrX:46798339-46907763 (-)
BALB/cJ MGP_BALBcJ_G0015715
 unclassified non-coding RNA gene ChrX:45158707-45253196 (-)
C3H/HeJ MGP_C3HHeJ_G0015535
 unclassified non-coding RNA gene ChrX:45986953-46062219 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016169
 unclassified non-coding RNA gene ChrX:46750012-46884950 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013893
 unclassified non-coding RNA gene ChrX:43176997-43246304 (-)
CAST/EiJ MGP_CASTEiJ_G0015090
 unclassified non-coding RNA gene ChrX:33407547-33506091 (-)
CBA/J MGP_CBAJ_G0015515
 unclassified non-coding RNA gene ChrX:48097713-48181076 (-)
DBA/2J MGP_DBA2J_G0015613
 unclassified non-coding RNA gene ChrX:45416304-45503413 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0015695
 unclassified non-coding RNA gene ChrX:46029865-46116289 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015641
 unclassified non-coding RNA gene ChrX:49597251-49712394 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0014872
 unclassified non-coding RNA gene ChrX:32889199-33034688 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014659
 unclassified non-coding RNA gene ChrX:34207416-34309204 (-)
WSB/EiJ MGP_WSBEiJ_G0015194
 unclassified non-coding RNA gene ChrX:45151966-45234739 (-)



Homology
more
  • Human Ortholog
    FIRRE, firre intergenic repeating RNA element
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FIRRE, firre intergenic repeating RNA element
  • Synonyms
    LINC01200
  • Links
    NCBI Gene ID: 286467

  • Chr Location
    Xq26.2; chrX:131688779-131830862 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    9 phenotype references
Mice homozygous for a null allele are viable and fertile with no defect in random or imprinted XCI.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1157
  • Tissues
    87
  • cDNA Data
    92
  • Literature Summary
    4
Sequences &
Gene Models
less
  • All Sequences
    56
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 103012 NCBI Gene Model | MGI Sequence Detail 72202 C57BL/6J ±  kb
transcript NR_015505 RefSeq | MGI Sequence Detail 5832 C57BL/6  
polypeptide Q3V1H2 UniProt | EBI | MGI Sequence Detail 85 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
Molecular
Reagents
less
  • All nucleic 92
    cDNA 92

    Microarray probesets 4
Other
Accession IDs
less
MGI:2442400
References
more
  • Summaries
    All 31
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 9
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:299861 Fang H, et al., Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome. Nat Commun. 2020 Nov 27;11(1):6053
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory