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Nudt10 Gene Detail
Summary
  • Symbol
    Nudt10
  • Name
    nudix hydrolase 10
  • Synonyms
    Dipp3a, DIPP3 alpha, nudix (nucleoside diphosphate linked moiety X)-type motif 10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147931
    NCBI Gene: 102954
  • Alliance
    genome feature page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:6080750-6085069 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 2.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    97 from dbSNP Build 142
  • Strain Annotations
    27
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147931
 protein coding gene ChrX:6080750-6085321 (-)
129S1/SvImJ ENSMUSG00200031240
 protein coding gene ChrX:780591-784910 (-)
129S1/SvImJ ENSMUSG00200030975
 protein coding gene ChrX:659343-667004 (+)
A/J ENSMUSG00195038574
 protein coding gene ChrX:803451-807771 (-)
A/J ENSMUSG00195038546
 protein coding gene ChrX:682214-689873 (+)
AKR/J ENSMUSG00220029753
 protein coding gene ChrX:663630-671289 (+)
AKR/J ENSMUSG00220029811
 protein coding gene ChrX:784868-789188 (-)
BALB/cJ ENSMUSG00180027654
 protein coding gene ChrX:780105-784424 (-)
BALB/cJ ENSMUSG00180027580
 protein coding gene ChrX:658875-666532 (+)
C3H/HeJ ENSMUSG00175028985
 protein coding gene ChrX:809947-814266 (-)
C3H/HeJ ENSMUSG00175028933
 protein coding gene ChrX:688714-696373 (+)
C57BL/6NJ ENSMUSG00215039132
 protein coding gene ChrX:1353117-1360774 (+)
C57BL/6NJ ENSMUSG00215039169
 protein coding gene ChrX:1474369-1478690 (-)
CAROLI/EiJ no annotation
CAST/EiJ ENSTCUG00005031930
 protein coding gene ChrX:749567-753918 (-)
CBA/J ENSMUSG00210032459
 protein coding gene ChrX:832113-836432 (-)
CBA/J ENSMUSG00210032433
 protein coding gene ChrX:710876-718535 (+)
DBA/2J ENSMUSG00185028086
 protein coding gene ChrX:7328003-7335660 (+)
DBA/2J ENSMUSG00185028104
 protein coding gene ChrX:7449246-7453565 (-)
FVB/NJ ENSMUSG00205023963
 protein coding gene ChrX:703379-711038 (+)
FVB/NJ ENSMUSG00205024060
 protein coding gene ChrX:824637-828957 (-)
JF1/MsJ no annotation
LP/J ENSMUSG00230027631
 protein coding gene ChrX:11969621-11973940 (-)
LP/J ENSMUSG00230027396
 protein coding gene ChrX:11848384-11856041 (+)
NOD/ShiLtJ ENSMUSG00190029212
 protein coding gene ChrX:666916-674564 (+)
NOD/ShiLtJ ENSMUSG00190029285
 protein coding gene ChrX:788475-792781 (-)
NZO/HlLtJ ENSMUSG00225045221
 protein coding gene ChrX:17113913-17121570 (+)
NZO/HlLtJ ENSMUSG00225045234
 protein coding gene ChrX:17235136-17239455 (-)
PWK/PhJ no annotation
SPRET/EiJ ENSMSPG00010022849
 protein coding gene ChrX:776706-781044 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    NUDT10, nudix hydrolase 10
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUDT10, nudix hydrolase 10
  • Synonyms
    APS2, DIPP3a, DIPP3-alpha
  • Links
    NCBI Gene ID: 170685
    UniProt: Q8NFP7

  • Chr Location
    Xp11.22; chrX:51332231-51337525 (+)  GRCh38
  • Human Ortholog
    NUDT11, nudix hydrolase 11
  • Synonyms
    APS1, ASP1, DIPP3b, DIPP3beta, hDIPP3beta
  • Links
    NCBI Gene ID: 55190
    UniProt: Q96G61

  • Chr Location
    Xp11.22; chrX:51490011-51496592 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype reference
Male mice hemizygous for a null allele exhibit normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073293 Ensembl Gene Model | MGI Sequence Detail 4320 C57BL/6J ±  kb
transcript ENSMUST00000103006 Ensembl | MGI Sequence Detail 1775 Not Applicable  
polypeptide ENSMUSP00000100071 Ensembl | MGI Sequence Detail 164 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • GlyGen
    P0C027 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Gene Ontology 9
    Phenotypes 1
  • Earliest
    J:84307 Hua LV, et al., Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases. Biochem J. 2003 Jul 1;373(Pt 1):81-9
  • Latest
    J:279039 Lu Y, et al., CRISPR/Cas9-mediated genome editing reveals 30 testis-enriched genes dispensable for male fertility in mice. Biol Reprod. 2019 Aug 1;101(2):501-511
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory