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Lipo3 Gene Detail
Summary
  • Symbol
    Lipo3
  • Name
    lipase, member O3
  • Synonyms
    Lipo1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2147592
    NCBI Gene: 381236
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr19:33532560-33568069 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 29.18 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2147592
 protein coding gene Chr19:33532560-33739351 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025045
 protein coding gene Chr19:32172537-32498550 (-)
A/J MGP_AJ_G0025024
 protein coding gene Chr19:30687915-30725348 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0025022
 protein coding gene Chr19:30720232-30816130 (-)
C3H/HeJ MGP_C3HHeJ_G0024777
 protein coding gene Chr19:31679669-32068756 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0022881
 protein coding gene Chr19:30382391-30384655 (-)
CAST/EiJ MGP_CASTEiJ_G0024248
 protein coding gene Chr19:31463124-31466371 (-)
CBA/J MGP_CBAJ_G0024755
 protein coding gene Chr19:34503163-34984721 (-)
DBA/2J MGP_DBA2J_G0024889
 protein coding gene Chr19:30508174-30816203 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0024973
 protein coding gene Chr19:32157532-32350022 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024879
 protein coding gene Chr19:34558026-34793877 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025521
 protein coding gene Chr19:31751479-32021770 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0023801
 protein coding gene Chr19:30966703-30970817 (-)
WSB/EiJ MGP_WSBEiJ_G0024314
 protein coding gene Chr19:31641755-31644048 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    6
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 381236 NCBI Gene Model | MGI Sequence Detail 35510 C57BL/6J ±  kb
transcript NM_001013770 RefSeq | MGI Sequence Detail 2854 C57BL/6  
polypeptide NP_001013792 RefSeq | MGI Sequence Detail 399 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR029058 Alpha/Beta hydrolase fold
    IPR025483 Lipase, eukaryotic
    IPR006693 Partial AB-hydrolase lipase domain
Molecular
Reagents
less
  • All nucleic 7
    cDNA 6
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 20
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:86696 Zambrowicz BP, et al., Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14109-14
  • Latest
    J:177709 Kooistra MK, et al., Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes. Physiol Genomics. 2012 Jan 18;44(1):35-46
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory