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Slc45a4 Gene Detail
Summary
  • Symbol
    Slc45a4
  • Name
    solute carrier family 45, member 4
  • Synonyms
    9330175B01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146236
    NCBI Gene: 106068
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:73449273-73517611 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.02 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1505 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146236
 protein coding gene Chr15:73449267-73517611 (-)
129S1/SvImJ ENSMUSG00200019337
 protein coding gene Chr15:70565800-70594368 (-)
A/J ENSMUSG00195027464
 protein coding gene Chr15:70622114-70650767 (-)
AKR/J ENSMUSG00220020352
 protein coding gene Chr15:70542682-70571336 (-)
BALB/cJ ENSMUSG00180021233
 protein coding gene Chr15:70394581-70423234 (-)
C3H/HeJ ENSMUSG00175005087
 protein coding gene Chr15:70751299-70779953 (-)
C57BL/6NJ ENSMUSG00215005591
 protein coding gene Chr15:70451740-70480394 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019864
 protein coding gene Chr15:67128575-67196749 (-)
CAST/EiJ ENSTCUG00005019226
 protein coding gene Chr15:70060045-70088648 (-)
CBA/J ENSMUSG00210024275
 protein coding gene Chr15:70531934-70560588 (-)
DBA/2J ENSMUSG00185023442
 protein coding gene Chr15:70479980-70508394 (-)
FVB/NJ ENSMUSG00205009635
 protein coding gene Chr15:70215338-70243992 (-)
JF1/MsJ ENSUMUG00000013674
 protein coding gene Chr15:70129527-70158097 (-)
LP/J ENSMUSG00230051568
 protein coding gene Chr15:73841439-73870091 (-)
NOD/ShiLtJ ENSMUSG00190004258
 protein coding gene Chr15:70593400-70621812 (-)
NZO/HlLtJ ENSMUSG00225052328
 protein coding gene Chr15:74120207-74148619 (-)
PWK/PhJ ENSLUMG00010010833
 protein coding gene Chr15:70411294-70439666 (-)
SPRET/EiJ ENSMSPG00010042880
 protein coding gene Chr15:72090939-72116070 (-)
WSB/EiJ ENSIUOG00005020107
 protein coding gene Chr15:70587997-70616545 (-)



Homology
more
  • Human Ortholog
    SLC45A4, solute carrier family 45 member 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC45A4, solute carrier family 45 member 4
  • Links
    NCBI Gene ID: 57210
    UniProt: Q5BKX6

  • Chr Location
    8q24.3; chr8:141207166-141308318 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotypes from 1 allele in 1 genetic background
    38 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display a transient white hair phenotype, increased thermal nociceptive threshold, abnormal nociceptor responses, and changes in polyamine homeostasis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    649
  • Tissues
    36
  • cDNA Data
    84
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000079020 Ensembl Gene Model | MGI Sequence Detail 68339 C57BL/6J ±  kb
    transcript ENSMUST00000054266 Ensembl | MGI Sequence Detail 4664 Not Applicable  
    polypeptide ENSMUSP00000054651 Ensembl | MGI Sequence Detail 793 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 88
      cDNA 84
      Primer pair 2
      Other 2

      Microarray probesets 7
    References
    more
    • Summaries
      All 69
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 9
      Phenotypes 38
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:387680 Ahn B, et al., Disorganization of Transcriptional Regulation and Alteration of Keratin Family Gene Expression in Hairy Ear Mice. Genes (Basel). 2026 Jan 31;17(2)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    09/08/2026
    MGI 6.24     		The Jackson Laboratory