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Lmf2 Gene Detail
Summary
  • Symbol
    Lmf2
  • Name
    lipase maturation factor 2
  • Synonyms
    Tmem112b, Tmem153
  • Feature Type
    protein coding gene
  • IDs
    MGI:2146015
    NCBI Gene: 105847
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:89235207-89239862 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 44.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    24 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2146015
 protein coding gene Chr15:89235203-89239862 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022227
 protein coding gene Chr15:90542295-90546950 (-)
A/J MGP_AJ_G0022186
 protein coding gene Chr15:87078227-87082882 (-)
AKR/J MGP_AKRJ_G0022161
 protein coding gene Chr15:89653122-89657777 (-)
BALB/cJ MGP_BALBcJ_G0022192
 protein coding gene Chr15:87182815-87187470 (-)
C3H/HeJ MGP_C3HHeJ_G0021962
 protein coding gene Chr15:89653794-89658449 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022637
 protein coding gene Chr15:93830267-93834922 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020162
 protein coding gene Chr15:83306316-83310969 (-)
CAST/EiJ MGP_CASTEiJ_G0021484
 protein coding gene Chr15:90429045-90433700 (-)
CBA/J MGP_CBAJ_G0021929
 protein coding gene Chr15:97016011-97020666 (-)
DBA/2J MGP_DBA2J_G0022056
 protein coding gene Chr15:86529297-86533952 (-)
FVB/NJ MGP_FVBNJ_G0022035
 protein coding gene Chr15:85594109-85598764 (-)
LP/J MGP_LPJ_G0022127
 protein coding gene Chr15:90699859-90704514 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022055
 protein coding gene Chr15:101413708-101418363 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022652
 protein coding gene Chr15:89691509-89696164 (-)
PWK/PhJ MGP_PWKPhJ_G0021225
 protein coding gene Chr15:86590723-86595378 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021059
 protein coding gene Chr15:89440434-89445082 (-)
WSB/EiJ MGP_WSBEiJ_G0021533
 protein coding gene Chr15:90180516-90185171 (-)



Homology
more
  • Human Ortholog
    LMF2, lipase maturation factor 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LMF2, lipase maturation factor 2
  • Synonyms
    TMEM112B, TMEM153
  • Links
    NCBI Gene ID: 91289
    neXtProt AC: NX_Q9BU23
    UniProt: Q9BU23

  • Chr Location
    22q13.33; chr22:50502949-50507702 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    24 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    2
  • Radiation induced
    2
  • Targeted
    1
  • Genomic Mutations
    3 involving Lmf2
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    20 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    99
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022614 Ensembl Gene Model | MGI Sequence Detail 4656 C57BL/6J ±  kb
transcript ENSMUST00000023283 Ensembl | MGI Sequence Detail 2906 Not Applicable  
polypeptide ENSMUSP00000023283 Ensembl | MGI Sequence Detail 702 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 99
    cDNA 99

    Microarray probesets 3
References
more
  • Summaries
    All 47
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 1
    Phenotypes 24
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory