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Aspg Gene Detail
Summary
  • Symbol
    Aspg
  • Name
    asparaginase
  • Synonyms
    A530050D06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2144822
    NCBI Gene: 104816
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:112073113-112093993 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 61.14 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    281 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2144822
protein coding gene Chr12:112073113-112094007 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020148
protein coding gene Chr12:114540148-114561038 (+)
A/J MGP_AJ_G0020104
protein coding gene Chr12:110126832-110148732 (+)
AKR/J MGP_AKRJ_G0020079
protein coding gene Chr12:113304428-113325361 (+)
BALB/cJ MGP_BALBcJ_G0020089
protein coding gene Chr12:110557510-110578400 (+)
C3H/HeJ MGP_C3HHeJ_G0019891
protein coding gene Chr12:113795102-113817525 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020534
protein coding gene Chr12:118090256-118111146 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018147
protein coding gene Chr12:106566587-106587602 (+)
CAST/EiJ MGP_CASTEiJ_G0019432
protein coding gene Chr12:108649739-108670798 (+)
CBA/J MGP_CBAJ_G0019858
protein coding gene Chr12:122602025-122629880 (+)
DBA/2J MGP_DBA2J_G0019975
protein coding gene Chr12:109612520-109633609 (+)
FVB/NJ MGP_FVBNJ_G0019960
protein coding gene Chr12:108416920-108438673 (+)
LP/J MGP_LPJ_G0020050
protein coding gene Chr12:114363969-114384859 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019998
protein coding gene Chr12:125710980-125731870 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020563
protein coding gene Chr12:112816541-112839765 (+)
PWK/PhJ MGP_PWKPhJ_G0019193
protein coding gene Chr12:104255035-104275923 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018996
protein coding gene Chr12:106977322-106998137 (+)
WSB/EiJ MGP_WSBEiJ_G0019491
protein coding gene Chr12:113715023-113737395 (+)



Homology
more
  • Human Ortholog
    ASPG, asparaginase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ASPG, asparaginase
  • Synonyms
    C14orf76, GPA/WT, hASNase1, LYSOLP
  • Links
    NCBI Gene ID: 374569
    neXtProt AC: NX_Q86U10
    UniProt: Q86U10

  • Chr Location
    14q32.33; chr14:104085686-104115582 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037686 Ensembl Gene Model | MGI Sequence Detail 20881 C57BL/6J ±  kb
transcript ENSMUST00000079400 Ensembl | MGI Sequence Detail 2722 Not Applicable  
polypeptide ENSMUSP00000078369 Ensembl | MGI Sequence Detail 564 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 3
Other
Accession IDs
less
MGI:2685536
References
more
  • Summaries
    All 34
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory