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Tmem266 Gene Detail
Summary
  • Symbol
    Tmem266
  • Name
    transmembrane protein 266
  • Synonyms
    AI118078
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142980
    NCBI Gene: 244886
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:55234197-55345629 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 29.98 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    3572 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142980
 protein coding gene Chr9:55234194-55345629 (+)
129S1/SvImJ ENSMUSG00200031641
 protein coding gene Chr9:52361670-52473108 (+)
A/J ENSMUSG00195035511
 protein coding gene Chr9:52059826-52171270 (+)
AKR/J ENSMUSG00220024261
 protein coding gene Chr9:52192739-52304164 (+)
BALB/cJ ENSMUSG00180015716
 protein coding gene Chr9:52173231-52284665 (+)
C3H/HeJ ENSMUSG00175020234
 protein coding gene Chr9:52184973-52296396 (+)
C57BL/6NJ ENSMUSG00215027690
 protein coding gene Chr9:52158336-52269764 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032245
 protein coding gene Chr9:52070111-52183030 (+)
CAST/EiJ ENSTCUG00005018432
 protein coding gene Chr9:52084894-52196046 (+)
CBA/J ENSMUSG00210031132
 protein coding gene Chr9:52279068-52390156 (+)
DBA/2J ENSMUSG00185036918
 protein coding gene Chr9:52317632-52429081 (+)
FVB/NJ ENSMUSG00205034440
 protein coding gene Chr9:52597489-52711482 (+)
JF1/MsJ ENSUMUG00000042828
 protein coding gene Chr9:52315779-52430403 (+)
LP/J ENSMUSG00230032486
 protein coding gene Chr9:52561633-52673061 (+)
NOD/ShiLtJ ENSMUSG00190039958
 protein coding gene Chr9:52375325-52489306 (+)
NZO/HlLtJ ENSMUSG00225027964
 protein coding gene Chr9:52583004-52696995 (+)
PWK/PhJ ENSLUMG00010036410
 protein coding gene Chr9:52278918-52399811 (+)
SPRET/EiJ ENSMSPG00010023296
 protein coding gene Chr9:53285441-53400329 (+)
WSB/EiJ ENSIUOG00005037191
 protein coding gene Chr9:51777201-51895231 (+)



Homology
more
  • Human Ortholog
    TMEM266, transmembrane protein 266
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM266, transmembrane protein 266
  • Synonyms
    C15orf27, HsHVRP1, hTMEM266, HVRP1
  • Links
    NCBI Gene ID: 123591
    UniProt: Q2M3C6

  • Chr Location
    15q24.2; chr15:76059936-76229121 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit reduced stereotypic counts in open-field test.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    26
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    10
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000032313 Ensembl Gene Model | MGI Sequence Detail 111433 C57BL/6J ±  kb
transcript ENSMUST00000034862 Ensembl | MGI Sequence Detail 2408 Not Applicable  
polypeptide ENSMUSP00000034862 Ensembl | MGI Sequence Detail 538 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Gene Ontology 8
    Phenotypes 6
  • Earliest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
  • Latest
    J:389864 Murata K, et al., A novel miniTurbo knock-in mouse reveals a protein interaction network of USP46 in the brain. Exp Anim. 2026 Jan 1;75(1):63-72
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory