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Strn4 Gene Detail
Summary
  • Symbol
    Strn4
  • Name
    striatin, calmodulin binding protein 4
  • Synonyms
    ZIN, zinedin
  • Feature Type
    protein coding gene
  • IDs
    MGI:2142346
    NCBI Gene: 97387
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:16549814-16574856 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    150 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2142346
protein coding gene Chr7:16549814-16574856 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031718
protein coding gene Chr7:14566286-14591604 (+)
A/J MGP_AJ_G0031690
protein coding gene Chr7:14295887-14320934 (+)
AKR/J MGP_AKRJ_G0031615
protein coding gene Chr7:14634044-14659065 (+)
BALB/cJ MGP_BALBcJ_G0031697
protein coding gene Chr7:14405136-14430168 (+)
C3H/HeJ MGP_C3HHeJ_G0031419
protein coding gene Chr7:14816014-14841859 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032163
protein coding gene Chr7:15302789-15327820 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029242
protein coding gene Chr7:15831774-15857060 (+)
CAST/EiJ MGP_CASTEiJ_G0030770
protein coding gene Chr7:11589385-11615139 (+)
CBA/J MGP_CBAJ_G0031378
protein coding gene Chr7:15797378-15822930 (+)
DBA/2J MGP_DBA2J_G0031534
protein coding gene Chr7:14185764-14211324 (+)
FVB/NJ MGP_FVBNJ_G0031490
protein coding gene Chr7:14084733-14111708 (+)
LP/J MGP_LPJ_G0031619
protein coding gene Chr7:14807141-14832453 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031525
protein coding gene Chr7:15730101-15755143 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032192
protein coding gene Chr7:14408177-14433200 (+)
PWK/PhJ MGP_PWKPhJ_G0030494
protein coding gene Chr7:11705038-11730578 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030321
protein coding gene Chr7:9336448-9361470 (+)
WSB/EiJ MGP_WSBEiJ_G0030867
protein coding gene Chr7:14479263-14505876 (+)



Homology
more
  • Human Ortholog
    STRN4, striatin 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STRN4, striatin 4
  • Synonyms
    PPP2R6C, ZIN, zinedin
  • Links
    NCBI Gene ID: 29888
    neXtProt AC: NX_Q9NRL3
    UniProt: Q9NRL3

  • Chr Location
    19q13.32; chr19:46719511-46746994 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 1 allele in 2 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic 97387 NCBI Gene Model | MGI Sequence Detail 25043 C57BL/6J ±  kb
    transcript NM_133789 RefSeq | MGI Sequence Detail 3562 C57BL/6  
    polypeptide P58404 UniProt | EBI | MGI Sequence Detail 760 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 151
      cDNA 151

      Microarray probesets 5
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 7
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    04/09/2024
    MGI 6.23
    The Jackson Laboratory