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Pramel32 Gene Detail
Summary
  • Symbol
    Pramel32
  • Name
    PRAME like 32
  • Synonyms
    C87499, MGC:60825
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140706
    NCBI Gene: 381590
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr4:88545557-88552423 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 42.02 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    25 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140706
 protein coding gene Chr4:88545557-88552648 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028426
 protein coding gene Chr4:88493537-88500583 (-)
A/J MGP_AJ_G0028387
 protein coding gene Chr4:85410158-85417031 (-)
AKR/J MGP_AKRJ_G0028336
 protein coding gene Chr4:87520409-87527242 (-)
BALB/cJ MGP_BALBcJ_G0028407
 protein coding gene Chr4:85619288-85628155 (-)
C3H/HeJ MGP_C3HHeJ_G0028120
 protein coding gene Chr4:88242659-88251585 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028846
 protein coding gene Chr4:91893532-91900377 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026145
 protein coding gene Chr4:81403475-81409996 (-)
CAST/EiJ MGP_CASTEiJ_G0027562
 protein coding gene Chr4:86081138-86088060 (-)
CBA/J MGP_CBAJ_G0028091
 protein coding gene Chr4:94708660-94715713 (-)
DBA/2J MGP_DBA2J_G0028240
 protein coding gene Chr4:85174207-85181106 (-)
FVB/NJ MGP_FVBNJ_G0028205
 protein coding gene Chr4:84123220-84130092 (-)
LP/J MGP_LPJ_G0028340
 protein coding gene Chr4:88854046-88860963 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028235
 protein coding gene Chr4:99720032-99727102 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028883
 protein coding gene Chr4:87661601-87668617 (-)
PWK/PhJ MGP_PWKPhJ_G0027285
 protein coding gene Chr4:83491106-83499419 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027108
 protein coding gene Chr4:85186071-85192471 (-)
WSB/EiJ MGP_WSBEiJ_G0027639
 protein coding gene Chr4:87867973-87876128 (-)



Homology
more
  • Human Ortholog
    PRAMEF1, PRAME family member 1
  • Vertebrate Orthologs
    21
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PRAMEF1, PRAME family member 1
  • Links
    NCBI Gene ID: 65121
    neXtProt AC: NX_O95521
    UniProt: O95521

  • Chr Location
    1p36.21; chr1:12791397-12796628 (+)  GRCh38
  • Human Ortholog
    PRAMEF10, PRAME family member 10
  • Links
    NCBI Gene ID: 343071
    neXtProt AC: NX_O60809
    UniProt: O60809

  • Chr Location
    1p36.21; chr1:12892896-12898270 (-)  GRCh38
  • Human Ortholog
    PRAMEF11, PRAME family member 11
  • Links
    NCBI Gene ID: 440560
    neXtProt AC: NX_O60813
    UniProt: O60813

  • Chr Location
    1p36.21; chr1:12824605-12831410 (-)  GRCh38
  • Human Ortholog
    PRAMEF12, PRAME family member 12
  • Links
    NCBI Gene ID: 390999
    neXtProt AC: NX_O95522
    UniProt: O95522

  • Chr Location
    1p36.21; chr1:12773738-12777906 (+)  GRCh38
  • Human Ortholog
    PRAMEF13, PRAME family member 13
  • Links
    NCBI Gene ID: 400736
    neXtProt AC: NX_Q5VWM6
    UniProt: Q5VWM6

  • Chr Location
    1p36.21; chr1:13196188-13201409 (-)  GRCh38
  • Human Ortholog
    PRAMEF17, PRAME family member 17
  • Links
    NCBI Gene ID: 391004
    neXtProt AC: NX_Q5VTA0
    UniProt: Q5VTA0

  • Chr Location
    1p36.21; chr1:13389632-13392629 (+)  GRCh38
  • Human Ortholog
    PRAMEF18, PRAME family member 18
  • Links
    NCBI Gene ID: 391003
    neXtProt AC: NX_Q5VWM3
    UniProt: Q5VWM3

  • Chr Location
    1p36.21; chr1:13222695-13226154 (-)  GRCh38
  • Human Ortholog
    PRAMEF19, PRAME family member 19
  • Links
    NCBI Gene ID: 645414
    neXtProt AC: NX_Q5SWL8
    UniProt: Q5SWL8

  • Chr Location
    1p36.21; chr1:13368431-13371947 (-)  GRCh38
  • Human Ortholog
    PRAMEF2, PRAME family member 2
  • Synonyms
    DJ845O24.3
  • Links
    NCBI Gene ID: 65122
    neXtProt AC: NX_O60811
    UniProt: O60811

  • Chr Location
    1p36.21; chr1:12857086-12861909 (+)  GRCh38
  • Human Ortholog
    PRAMEF20, PRAME family member 20
  • Synonyms
    PRAMEF21
  • Links
    NCBI Gene ID: 645425
    neXtProt AC: NX_Q5VT98
    UniProt: Q5VT98

  • Chr Location
    1p36.21; chr1:13410450-13421328 (+)  GRCh38
  • Human Ortholog
    PRAMEF25, PRAME family member 25
  • Links
    NCBI Gene ID: 441873
    neXtProt AC: NX_A6NGN4
    UniProt: A6NGN4

  • Chr Location
    1p36.21; chr1:13068677-13077884 (+)  GRCh38
  • Human Ortholog
    PRAMEF26, PRAME family member 26
  • Synonyms
    PRAMEF25
  • Links
    NCBI Gene ID: 645359
    neXtProt AC: NX_A6NGN4
    UniProt: H0Y7S4

  • Chr Location
    1p36.21
  • Human Ortholog
    PRAMEF27, PRAME family member 27
  • Links
    NCBI Gene ID: 101929983
    neXtProt AC: NX_A3QJZ7
    UniProt: A3QJZ7

  • Chr Location
    chr1:13049476-13056575 (-)  GRCh38
  • Human Ortholog
    PRAMEF33, PRAME family member 33
  • Synonyms
    PRAMEF33P
  • Links
    NCBI Gene ID: 645382
    neXtProt AC: NX_A0A0G2JMD5
    UniProt: A0A0G2JMD5

  • Chr Location
    1p36.21; chr1:13303539-13308907 (+)  GRCh38
  • Human Ortholog
    PRAMEF4, PRAME family member 4
  • Links
    NCBI Gene ID: 400735
    neXtProt AC: NX_O60810
    UniProt: O60810

  • Chr Location
    1p36.21; chr1:12879212-12886201 (-)  GRCh38
  • Human Ortholog
    PRAMEF5, PRAME family member 5
  • Synonyms
    PRAMEF23, PRAMEF5L
  • Links
    NCBI Gene ID: 343068
    neXtProt AC: NX_Q5TYX0
    UniProt: Q5TYX0

  • Chr Location
    1p36.21; chr1:13254198-13263435 (+)  GRCh38
  • Human Ortholog
    PRAMEF6, PRAME family member 6
  • Links
    NCBI Gene ID: 440561
    neXtProt AC: NX_Q5VXH4
    UniProt: Q5VXH4

  • Chr Location
    1p36.21; chr1:12938472-12947580 (-)  GRCh38
  • Human Ortholog
    PRAMEF7, PRAME family member 7
  • Links
    NCBI Gene ID: 441871
    neXtProt AC: NX_Q5VXH5
    UniProt: Q5VXH5

  • Chr Location
    1p36.21; chr1:12916610-12920751 (+)  GRCh38
  • Human Ortholog
    PRAMEF8, PRAME family member 8
  • Synonyms
    PRAMEF24
  • Links
    NCBI Gene ID: 391002
    neXtProt AC: NX_Q5VWM4
    UniProt: Q5VWM4

  • Chr Location
    1p36.21; chr1:13281304-13285137 (-)  GRCh38
  • Human Ortholog
    PRAMEF9, PRAME family member 9
  • Links
    NCBI Gene ID: 343070
    UniProt: P0DUQ2

  • Chr Location
    1p36.21; chr1:13171848-13179459 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PRAME associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    5 involving Pramel32
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    42 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    46
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 381590 NCBI Gene Model | MGI Sequence Detail 6867 C57BL/6J ±  kb
transcript NM_198663 RefSeq | MGI Sequence Detail 1828 C57BL/6  
polypeptide NP_941065 RefSeq | MGI Sequence Detail 493 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • InterPro Domains
    IPR032675 Leucine-rich repeat domain superfamily
    IPR026271 PRAME
Molecular
Reagents
less
  • All nucleic 47
    Genomic 1
    cDNA 46

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Gene Ontology 2
    Phenotypes 7
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:235276 Saito M, et al., Identification of Stmm3 locus conferring resistance to late-stage chemically induced skin papillomas on mouse chromosome 4 by congenic mapping and allele-specific alteration analysis. Exp Anim. 2014;63(3):339-48
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory