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Dcaf10 Gene Detail
Summary
  • Symbol
    Dcaf10
  • Name
    DDB1 and CUL4 associated factor 10
  • Synonyms
    Wdr32
  • Feature Type
    protein coding gene
  • IDs
    MGI:2140179
    NCBI Gene: 242418
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:45342101-45379759 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 23.87 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    168 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2140179
 protein coding gene Chr4:45340764-45379759 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028244
 protein coding gene Chr4:43572584-43612112 (+)
A/J MGP_AJ_G0028202
 protein coding gene Chr4:42011813-42050055 (+)
AKR/J MGP_AKRJ_G0028153
 protein coding gene Chr4:43012551-43050219 (+)
BALB/cJ MGP_BALBcJ_G0028222
 protein coding gene Chr4:42091666-42130180 (+)
C3H/HeJ MGP_C3HHeJ_G0027943
 protein coding gene Chr4:43617520-43661522 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028663
 protein coding gene Chr4:45211732-45253758 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025972
 protein coding gene Chr4:39402048-39440788 (+)
CAST/EiJ MGP_CASTEiJ_G0027383
 protein coding gene Chr4:43165399-43204585 (+)
CBA/J MGP_CBAJ_G0027909
 protein coding gene Chr4:46619024-46660365 (+)
DBA/2J MGP_DBA2J_G0028059
 protein coding gene Chr4:41906569-41944334 (+)
FVB/NJ MGP_FVBNJ_G0028026
 protein coding gene Chr4:41138084-41176671 (+)
LP/J MGP_LPJ_G0028158
 protein coding gene Chr4:43620490-43660705 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028050
 protein coding gene Chr4:49759900-49806504 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028698
 protein coding gene Chr4:43225257-43266463 (+)
PWK/PhJ MGP_PWKPhJ_G0027107
 protein coding gene Chr4:41977369-42015776 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026935
 protein coding gene Chr4:42732762-42773963 (+)
WSB/EiJ MGP_WSBEiJ_G0027460
 protein coding gene Chr4:43116791-43154931 (+)



Homology
more
  • Human Ortholog
    DCAF10, DDB1 and CUL4 associated factor 10
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCAF10, DDB1 and CUL4 associated factor 10
  • Synonyms
    WDR32
  • Links
    NCBI Gene ID: 79269
    neXtProt AC: NX_Q5QP82
    UniProt: Q5QP82

  • Chr Location
    9p13.2; chr9:37800554-37867666 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    767
  • Tissues
    50
  • cDNA Data
    68
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000035572 Ensembl Gene Model | MGI Sequence Detail 37659 C57BL/6J ±  kb
transcript ENSMUST00000155551 Ensembl | MGI Sequence Detail 7250 Not Applicable  
polypeptide ENSMUSP00000117082 Ensembl | MGI Sequence Detail 566 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 69
    cDNA 68
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 7
  • Earliest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
  • Latest
    J:266543 Zhang YL, et al., DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development. EMBO J. 2018 Sep 14;37(18)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory