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Ctso Gene Detail
Summary
  • Symbol
    Ctso
  • Name
    cathepsin O
  • Synonyms
    A330105D01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139628
    NCBI Gene: 229445
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:81839908-81864032 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 3, 35.97 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    350 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139628
protein coding gene Chr3:81839908-81864032 (+)
129S1/SvImJ MGP_129S1SvImJ_G0027322
protein coding gene Chr3:81722576-81751428 (+)
A/J MGP_AJ_G0027284
protein coding gene Chr3:79018311-79043542 (+)
AKR/J MGP_AKRJ_G0027252
protein coding gene Chr3:80888618-80912643 (+)
BALB/cJ MGP_BALBcJ_G0027295
protein coding gene Chr3:79119614-79144940 (+)
C3H/HeJ MGP_C3HHeJ_G0027039
protein coding gene Chr3:81173229-81198226 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027741
protein coding gene Chr3:84833066-84858414 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025094
protein coding gene Chr3:74784289-74810331 (+)
CAST/EiJ MGP_CASTEiJ_G0026486
protein coding gene Chr3:81345700-81370426 (+)
CBA/J MGP_CBAJ_G0027014
protein coding gene Chr3:87667685-87694231 (+)
DBA/2J MGP_DBA2J_G0027150
protein coding gene Chr3:78578776-78603495 (+)
FVB/NJ MGP_FVBNJ_G0027118
protein coding gene Chr3:76866993-76890885 (+)
LP/J MGP_LPJ_G0027258
protein coding gene Chr3:82725241-82750251 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027137
protein coding gene Chr3:94052706-94076791 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027799
protein coding gene Chr3:80687370-80712536 (+)
PWK/PhJ MGP_PWKPhJ_G0026220
protein coding gene Chr3:78310547-78334536 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026036
protein coding gene Chr3:79904177-79928298 (+)
WSB/EiJ MGP_WSBEiJ_G0026564
protein coding gene Chr3:81033431-81057907 (+)



Homology
more
  • Human Ortholog
    CTSO, cathepsin O
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CTSO, cathepsin O
  • Synonyms
    CTSO1
  • Links
    NCBI Gene ID: 1519
    neXtProt AC: NX_P43234
    UniProt: P43234

  • Chr Location
    4q32.1; chr4:155921580-155953912 (-)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 229445 NCBI Gene Model | MGI Sequence Detail 24125 C57BL/6J ±  kb
    transcript NM_177662 RefSeq | MGI Sequence Detail 3468 C57BL/6  
    polypeptide Q8BM88 UniProt | EBI | MGI Sequence Detail 312 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 57
      Genomic 1
      cDNA 56

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1925015
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 3
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory