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Scrt2 Gene Detail
Summary
  • Symbol
    Scrt2
  • Name
    scratch family zinc finger 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139287
    NCBI Gene: 545474
  • Alliance
    gene page
  • Transcription Start Sites
    18 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:151923737-151937722 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 74.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    87 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139287
 protein coding gene Chr2:151923449-151937722 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026650
 protein coding gene Chr2:156606643-156620892 (+)
A/J MGP_AJ_G0026616
 protein coding gene Chr2:150363710-150377922 (+)
AKR/J MGP_AKRJ_G0026586
 protein coding gene Chr2:154748810-154763034 (+)
BALB/cJ MGP_BALBcJ_G0026625
 protein coding gene Chr2:150679023-150693242 (+)
C3H/HeJ MGP_C3HHeJ_G0026368
 protein coding gene Chr2:155138940-155153157 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027074
 protein coding gene Chr2:161169622-161183895 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024445
 protein coding gene Chr2:143970473-143984837 (+)
CAST/EiJ MGP_CASTEiJ_G0025829
 protein coding gene Chr2:155365680-155383674 (+)
CBA/J MGP_CBAJ_G0026346
 protein coding gene Chr2:167067565-167083163 (+)
DBA/2J MGP_DBA2J_G0026482
 protein coding gene Chr2:149584196-149598405 (+)
FVB/NJ MGP_FVBNJ_G0026447
 protein coding gene Chr2:148018921-148033150 (+)
LP/J MGP_LPJ_G0026586
 protein coding gene Chr2:156763213-156777481 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026469
 protein coding gene Chr2:171210473-171224730 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027129
 protein coding gene Chr2:154631117-154645285 (+)
PWK/PhJ MGP_PWKPhJ_G0025563
 protein coding gene Chr2:149106643-149120960 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025366
 protein coding gene Chr2:153471690-153486087 (+)
WSB/EiJ MGP_WSBEiJ_G0025899
 protein coding gene Chr2:155560752-155576297 (+)



Homology
more
  • Human Ortholog
    SCRT2, scratch family transcriptional repressor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCRT2, scratch family transcriptional repressor 2
  • Synonyms
    ZNF898B
  • Links
    NCBI Gene ID: 85508
    neXtProt AC: NX_Q9NQ03
    UniProt: Q9NQ03

  • Chr Location
    20p13; chr20:661596-675802 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    6
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    1
  • Genomic Mutations
    2 involving Scrt2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    15 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    947
  • Tissues
    91
  • cDNA Data
    9
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 545474 NCBI Gene Model | MGI Sequence Detail 13986 C57BL/6J ±  kb
transcript NM_001160410 RefSeq | MGI Sequence Detail 3107 C57BL/6  
polypeptide Q8BTH6 UniProt | EBI | MGI Sequence Detail 311 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
References
more
  • Summaries
    All 34
    Developmental Gene Expression 8
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:314103 Ulmke PA, et al., Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Stem Cell Reports. 2021 Apr 13;16(4):968-984
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory