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Osbpl6 Gene Detail
Summary
  • Symbol
    Osbpl6
  • Name
    oxysterol binding protein-like 6
  • Synonyms
    1110062M20Rik, ORP-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139014
    NCBI Gene: 99031
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:76236852-76430991 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 44.94 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2135 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139014
 protein coding gene Chr2:76236848-76430991 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025865
 protein coding gene Chr2:76805132-76995091 (+)
A/J MGP_AJ_G0025842
 protein coding gene Chr2:73815472-74003044 (+)
AKR/J MGP_AKRJ_G0025811
 protein coding gene Chr2:75798481-75993910 (+)
BALB/cJ MGP_BALBcJ_G0025837
 protein coding gene Chr2:73994714-74182394 (+)
C3H/HeJ MGP_C3HHeJ_G0025597
 protein coding gene Chr2:76014530-76202501 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026284
 protein coding gene Chr2:79075040-79277040 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023687
 protein coding gene Chr2:71221853-71408460 (+)
CAST/EiJ MGP_CASTEiJ_G0025059
 protein coding gene Chr2:76345709-76536851 (+)
CBA/J MGP_CBAJ_G0025578
 protein coding gene Chr2:82006475-82211721 (+)
DBA/2J MGP_DBA2J_G0025709
 protein coding gene Chr2:73406774-73594950 (+)
FVB/NJ MGP_FVBNJ_G0025671
 protein coding gene Chr2:72778633-72985916 (+)
LP/J MGP_LPJ_G0025797
 protein coding gene Chr2:76682958-76876515 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025702
 protein coding gene Chr2:83837746-84029799 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026340
 protein coding gene Chr2:75923166-76119219 (+)
PWK/PhJ MGP_PWKPhJ_G0024802
 protein coding gene Chr2:73362061-73554033 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024608
 protein coding gene Chr2:76169601-76360760 (+)
WSB/EiJ MGP_WSBEiJ_G0025128
 protein coding gene Chr2:76382730-76583801 (+)



Homology
more
  • Human Ortholog
    OSBPL6, oxysterol binding protein like 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OSBPL6, oxysterol binding protein like 6
  • Synonyms
    ORP6
  • Links
    NCBI Gene ID: 114880
    neXtProt AC: NX_Q9BZF3
    UniProt: Q9BZF3

  • Chr Location
    2q31.2; chr2:178193774-178402893 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    990
  • Tissues
    55
  • cDNA Data
    42
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042359 Ensembl Gene Model | MGI Sequence Detail 194140 C57BL/6J ±  kb
transcript ENSMUST00000077972 Ensembl | MGI Sequence Detail 8037 Not Applicable  
polypeptide ENSMUSP00000077123 Ensembl | MGI Sequence Detail 967 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 47
    cDNA 42
    Primer pair 3
    Other 2

    Microarray probesets 10
Other
Accession IDs
less
MGI:1916103
References
more
  • Summaries
    All 41
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:327901 Ye Q, et al., Understanding the development of oral epithelial organs through single cell transcriptomic analysis. Development. 2022 Aug 15;149(16):dev200539
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory