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Eeig1 Gene Detail
Summary
  • Symbol
    Eeig1
  • Name
    estrogen-induced osteoclastogenesis regulator 1
  • Synonyms
    C230093N12Rik, Fam102a
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138935
    NCBI Gene: 98952
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:32425344-32459763 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 22.09 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1256 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138935
 protein coding gene Chr2:32425344-32459768 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025609
 protein coding gene Chr2:31006562-31044200 (+)
A/J MGP_AJ_G0025586
 protein coding gene Chr2:29682566-29717097 (+)
AKR/J MGP_AKRJ_G0025556
 protein coding gene Chr2:30747933-30782170 (+)
BALB/cJ MGP_BALBcJ_G0025583
 protein coding gene Chr2:29807501-29842477 (+)
C3H/HeJ MGP_C3HHeJ_G0025343
 protein coding gene Chr2:30636975-30671849 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026027
 protein coding gene Chr2:31948786-31984890 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023436
 protein coding gene Chr2:28402487-28437108 (+)
CAST/EiJ MGP_CASTEiJ_G0024805
 protein coding gene Chr2:30576401-30611006 (+)
CBA/J MGP_CBAJ_G0025321
 protein coding gene Chr2:33159217-33202172 (+)
DBA/2J MGP_DBA2J_G0025454
 protein coding gene Chr2:29451166-29485394 (+)
FVB/NJ MGP_FVBNJ_G0025416
 protein coding gene Chr2:29324860-29360403 (+)
LP/J MGP_LPJ_G0025540
 protein coding gene Chr2:30877172-30919969 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025447
 protein coding gene Chr2:32800366-32835097 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026085
 protein coding gene Chr2:30625601-30660793 (+)
PWK/PhJ MGP_PWKPhJ_G0024553
 protein coding gene Chr2:29354892-29390542 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024353
 protein coding gene Chr2:30780341-30815534 (+)
WSB/EiJ MGP_WSBEiJ_G0024874
 protein coding gene Chr2:30802766-30837153 (+)



Homology
more
  • Human Ortholog
    EEIG1, estrogen-induced osteoclastogenesis regulator 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EEIG1, estrogen-induced osteoclastogenesis regulator 1
  • Synonyms
    bA203J24.7, C9orf132, FAM102A, SYM-3A
  • Links
    NCBI Gene ID: 399665
    UniProt: Q5T9C2

  • Chr Location
    chr9:127940582-127980989 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous knockout reduces susceptibility to inflammation-induced bone resorption by suppressing osteoclast formation.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    770
  • Tissues
    9
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 98952 NCBI Gene Model | MGI Sequence Detail 34420 C57BL/6J ±  kb
transcript NM_153560 RefSeq | MGI Sequence Detail 4245 C57BL/6  
polypeptide Q78T81 UniProt | EBI | MGI Sequence Detail 392 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 4
Other
Accession IDs
less
MGI:7388572
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Phenotypes 5
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:361090 Yamashita Y, et al., Fam102a translocates Runx2 and Rbpjl to facilitate Osterix expression and bone formation. Nat Commun. 2025 Jan 2;16(1):9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory