About   Help   FAQ
Slc5a12 Gene Detail
Summary
  • Symbol
    Slc5a12
  • Name
    solute carrier family 5 (sodium/glucose cotransporter), member 12
  • Synonyms
    SMCT2
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138890
    NCBI Gene: 241612
  • Alliance
    genome feature page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:110427643-110478124 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 56.75 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1693 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138890
 protein coding gene Chr2:110427643-110479690 (+)
129S1/SvImJ ENSMUSG00200006572
 protein coding gene Chr2:107312213-107369926 (+)
A/J ENSMUSG00195030116
 protein coding gene Chr2:107386483-107444209 (+)
AKR/J ENSMUSG00220004415
 protein coding gene Chr2:107234252-107284767 (+)
BALB/cJ ENSMUSG00180029947
 protein coding gene Chr2:107181649-107239366 (+)
C3H/HeJ ENSMUSG00175030946
 protein coding gene Chr2:107577071-107626650 (+)
C57BL/6NJ ENSMUSG00215018460
 protein coding gene Chr2:107321637-107372127 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024053
 protein coding gene Chr2:103722721-103771806 (+)
CAST/EiJ ENSTCUG00005005345
 protein coding gene Chr2:106579602-106630028 (+)
CBA/J ENSMUSG00210033519
 protein coding gene Chr2:107455802-107513517 (+)
DBA/2J ENSMUSG00185037311
 protein coding gene Chr2:107178078-107235801 (+)
FVB/NJ ENSMUSG00205015549
 protein coding gene Chr2:106484294-106542015 (+)
JF1/MsJ ENSUMUG00000001659
 protein coding gene Chr2:106978714-107028310 (+)
LP/J ENSMUSG00230005209
 protein coding gene Chr2:108974538-109032258 (+)
NOD/ShiLtJ ENSMUSG00190014504
 protein coding gene Chr2:107399560-107457248 (+)
NZO/HlLtJ ENSMUSG00225012324
 protein coding gene Chr2:116874483-116932183 (+)
PWK/PhJ ENSLUMG00010002969
 protein coding gene Chr2:106959924-107009430 (+)
SPRET/EiJ ENSMSPG00010032532
 protein coding gene Chr2:109173717-109233216 (+)
WSB/EiJ ENSIUOG00005031726
 protein coding gene Chr2:107064740-107115256 (+)



Homology
more
  • Human Ortholog
    SLC5A12, solute carrier family 5 member 12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC5A12, solute carrier family 5 member 12
  • Synonyms
    SMCT2
  • Links
    NCBI Gene ID: 159963
    UniProt: Q1EHB4

  • Chr Location
    11p14.2; chr11:26667020-26723427 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    600
  • Tissues
    3
  • cDNA Data
    12
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041644 Ensembl Gene Model | MGI Sequence Detail 50482 C57BL/6J ±  kb
transcript ENSMUST00000045972 Ensembl | MGI Sequence Detail 3529 Not Applicable  
polypeptide ENSMUSP00000047340 Ensembl | MGI Sequence Detail 623 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 12
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 46
    Developmental Gene Expression 2
    Gene Ontology 10
    Phenotypes 12
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/08/2026
MGI 6.24 		The Jackson Laboratory