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Sh3bp4 Gene Detail
Summary
  • Symbol
    Sh3bp4
  • Name
    SH3-domain binding protein 4
  • Synonyms
    BOG25
  • Feature Type
    protein coding gene
  • IDs
    MGI:2138297
    NCBI Gene: 98402
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:88998137-89082790 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 45.05 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    676 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2138297
 protein coding gene Chr1:88998061-89082809 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016289
 protein coding gene Chr1:90520717-90601424 (+)
A/J MGP_AJ_G0016270
 protein coding gene Chr1:87269155-87348105 (+)
AKR/J MGP_AKRJ_G0016231
 protein coding gene Chr1:89850191-89931549 (+)
BALB/cJ MGP_BALBcJ_G0016226
 protein coding gene Chr1:87412431-87492715 (+)
C3H/HeJ MGP_C3HHeJ_G0016055
 protein coding gene Chr1:90065209-90146092 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016685
 protein coding gene Chr1:94035765-94122648 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014403
 protein coding gene Chr1:81562368-81643107 (+)
CAST/EiJ MGP_CASTEiJ_G0015640
 protein coding gene Chr1:89378098-89463614 (+)
CBA/J MGP_CBAJ_G0016031
 protein coding gene Chr1:97021195-97103213 (+)
DBA/2J MGP_DBA2J_G0016134
 protein coding gene Chr1:86492317-86572180 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0016205
 protein coding gene Chr1:91660032-91741119 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016158
 protein coding gene Chr1:100359074-100438499 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016725
 protein coding gene Chr1:89877914-89956810 (+)
PWK/PhJ MGP_PWKPhJ_G0015424
 protein coding gene Chr1:85889873-85970100 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015207
 protein coding gene Chr1:88766485-88850150 (+)
WSB/EiJ MGP_WSBEiJ_G0015698
 protein coding gene Chr1:89592664-89673026 (+)



Homology
more
  • Human Ortholog
    SH3BP4, SH3 domain binding protein 4
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SH3BP4, SH3 domain binding protein 4
  • Synonyms
    BOG25, TTP
  • Links
    NCBI Gene ID: 23677
    neXtProt AC: NX_Q9P0V3
    UniProt: Q9P0V3

  • Chr Location
    2q37.2; chr2:234952017-235055714 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    727
  • Tissues
    3
  • cDNA Data
    12
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000036206 Ensembl Gene Model | MGI Sequence Detail 84654 C57BL/6J ±  kb
    transcript ENSMUST00000066279 Ensembl | MGI Sequence Detail 4995 Not Applicable  
    polypeptide ENSMUSP00000067581 Ensembl | MGI Sequence Detail 962 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 13
      cDNA 13

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2138581
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 18
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory