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Trim9 Gene Detail
Summary
  • Symbol
    Trim9
  • Name
    tripartite motif-containing 9
  • Synonyms
    C030048G07Rik, mKIAA0282
  • Feature Type
    protein coding gene
  • IDs
    MGI:2137354
    NCBI Gene: 94090
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:70291307-70394388 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 12, 29.07 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3043 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2137354
protein coding gene Chr12:70291307-70394404 (-)
129S1/SvImJ ENSMUSG00200029156
protein coding gene Chr12:62211102-62314227 (-)
A/J ENSMUSG00195013892
protein coding gene Chr12:64906772-65011011 (-)
AKR/J ENSMUSG00220014427
protein coding gene Chr12:62709153-62812249 (-)
BALB/cJ ENSMUSG00180033031
protein coding gene Chr12:63905853-64010083 (-)
C3H/HeJ ENSMUSG00175027539
protein coding gene Chr12:67000216-67104440 (-)
C57BL/6NJ ENSMUSG00215022300
protein coding gene Chr12:63280458-63383553 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017819
protein coding gene Chr12:64904570-65008050 (-)
CAST/EiJ ENSTCUG00005032886
protein coding gene Chr12:63235907-63339934 (-)
CBA/J ENSMUSG00210027039
protein coding gene Chr12:63470217-63574438 (-)
DBA/2J ENSMUSG00185004639
protein coding gene Chr12:65369600-65473810 (-)
FVB/NJ ENSMUSG00205024938
protein coding gene Chr12:63111724-63215944 (-)
JF1/MsJ ENSUMUG00000014450
protein coding gene Chr12:69329870-69433569 (-)
LP/J ENSMUSG00230015113
protein coding gene Chr12:72336764-72439846 (-)
NOD/ShiLtJ ENSMUSG00190011679
protein coding gene Chr12:62525538-62628633 (-)
NZO/HlLtJ ENSMUSG00225037778
protein coding gene Chr12:74413112-74516707 (-)
PWK/PhJ ENSLUMG00010028847
protein coding gene Chr12:63402083-63504055 (-)
SPRET/EiJ ENSMSPG00010026654
protein coding gene Chr12:65084737-65189674 (-)
WSB/EiJ ENSIUOG00005011596
protein coding gene Chr12:63164076-63267194 (-)



Homology
more
  • Human Ortholog
    TRIM9, tripartite motif containing 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRIM9, tripartite motif containing 9
  • Synonyms
    RNF91, SPRING
  • Links
    NCBI Gene ID: 114088
    UniProt: Q9C026

  • Chr Location
    14q22.1; chr14:50975261-51096078 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    16 phenotypes from 2 alleles in 3 genetic backgrounds
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation display increased axonal branching and increased corpus callosum thickness.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
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    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000021071 Ensembl Gene Model | MGI Sequence Detail 103082 C57BL/6J ±  kb
    transcript ENSMUST00000222316 Ensembl | MGI Sequence Detail 3049 Not Applicable  
    polypeptide ENSMUSP00000152147 Ensembl | MGI Sequence Detail 817 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 73
      cDNA 67
      Primer pair 4
      Other 2
      Antibodies 4

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1924734, MGI:2144887
    References
    more
    • Summaries
      All 68
      Developmental Gene Expression 16
      Gene Ontology 12
      Phenotypes 20
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:387961 Mutalik SP, et al., TRIM9 Controls Growth Cone Responses to Netrin Through DCC and UNC5C. J Neurochem. 2025 Jan;169(1):e70002

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    09/08/2026
    MGI 6.24
    The Jackson Laboratory