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Pcdhb19 Gene Detail
Summary
  • Symbol
    Pcdhb19
  • Name
    protocadherin beta 19
  • Synonyms
    Pcdhb11, PcdhbS
Location &
Maps
more
  • Sequence Map
    Chr18:37630049-37637181 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 19.51 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    358 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136757
 protein coding gene Chr18:37630044-37637181 (+)
129S1/SvImJ ENSMUSG00200042553
 protein coding gene Chr18:34619249-34626398 (+)
A/J ENSMUSG00195034860
 protein coding gene Chr18:34780766-34787909 (+)
AKR/J ENSMUSG00220016189
 protein coding gene Chr18:34762362-34769514 (+)
BALB/cJ ENSMUSG00180015444
 protein coding gene Chr18:35230388-35237531 (+)
C3H/HeJ ENSMUSG00175034747
 protein coding gene Chr18:34752515-34759661 (+)
C57BL/6NJ ENSMUSG00215019522
 protein coding gene Chr18:34499571-34506714 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022175
 protein coding gene Chr18:34718369-34725825 (+)
CAST/EiJ ENSTCUG00005021483
 protein coding gene Chr18:34371455-34378565 (+)
CBA/J ENSMUSG00210021101
 protein coding gene Chr18:34772408-34779548 (+)
DBA/2J ENSMUSG00185017463
 protein coding gene Chr18:34707045-34714188 (+)
FVB/NJ ENSMUSG00205024388
 protein coding gene Chr18:34424159-34431311 (+)
JF1/MsJ ENSUMUG00000045020
 protein coding gene Chr18:34843559-34850698 (+)
LP/J ENSMUSG00230043195
 protein coding gene Chr18:36815917-36823066 (+)
NOD/ShiLtJ ENSMUSG00190017327
 protein coding gene Chr18:34500815-34507967 (+)
NZO/HlLtJ ENSMUSG00225045630
 protein coding gene Chr18:36722592-36729726 (+)
PWK/PhJ ENSLUMG00010011663
 protein coding gene Chr18:35009672-35016814 (+)
SPRET/EiJ ENSMSPG00010021832
 protein coding gene Chr18:35046534-35053635 (+)
WSB/EiJ ENSIUOG00005006845
 protein coding gene Chr18:34477584-34484724 (+)



Homology
more
  • Human Ortholog
    PCDHB11, protocadherin beta 11
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCDHB11, protocadherin beta 11
  • Synonyms
    ME2, PCDH-BETA11
  • Links
    NCBI Gene ID: 56125
    UniProt: Q9Y5F2

  • Chr Location
    5q31.3; chr5:141199610-141203779 (+)  GRCh38
  • Human Ortholog
    PCDHB12, protocadherin beta 12
  • Synonyms
    PCDH-BETA12
  • Links
    NCBI Gene ID: 56124
    UniProt: Q9Y5F1

  • Chr Location
    5q31.3; chr5:141208697-141212571 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    655
  • Tissues
    35
  • cDNA Data
    13
  • Literature Summary
    6
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93890 NCBI Gene Model | MGI Sequence Detail 7133 C57BL/6J ±  kb
transcript NM_053144 RefSeq | MGI Sequence Detail 7133 C57BL/6  
polypeptide NP_444374 RefSeq | MGI Sequence Detail 801 C57BL/6  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 13
    Primer pair 4

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 6
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:86878 Wu Q, et al., A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 1999 Jun 11;97(6):779-90
  • Latest
    J:332241 Kobayashi H, et al., Isoform requirement of clustered protocadherin for preventing neuronal apoptosis and neonatal lethality. iScience. 2023 Jan 20;26(1):105766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory